Results 51 to 60 of about 4,732,881 (277)

Chinese pediatric Tuina on children with acute diarrhea: a randomized sham-controlled trial

open access: yesHealth and Quality of Life Outcomes, 2021
Background Pediatric Tuina has been widely used in children with acute diarrhea in China. However, due to the lack of high-quality clinical evidence, the benefit of Tuina as a therapy is not clear.
Taoying Lu   +13 more
doaj   +1 more source

Measuring functional outcomes in schizophrenia in an increasingly digital world

open access: yesSchizophrenia Research: Cognition, 2022
With an unmet clinical need for effective interventions for cognitive and negative symptoms in patients with schizophrenia, measures of functional status (often a co-primary endpoint) remain key clinical trial outcomes.
Anja Searle   +4 more
doaj   +1 more source

Protocol for the Foot in Juvenile Idiopathic Arthritis trial (FiJIA): a randomised controlled trial of an integrated foot care programme for foot problems in JIA [PDF]

open access: yes, 2009
<b>Background</b>: Foot and ankle problems are a common but relatively neglected manifestation of juvenile idiopathic arthritis. Studies of medical and non-medical interventions have shown that clinical outcome measures can be improved ...
A Manca   +60 more
core   +4 more sources

Clinical Outcome Assessments in Encephalitis

open access: yesNeurology Neuroimmunology & Neuroinflammation
Most patients with encephalitis experience persisting neurocognitive and neuropsychiatric sequelae in the years following this acute illness. Reported outcomes are often based on generic clinical outcome assessments that rarely capture the patient perspective. This may result in an underestimation of disease-specific sequelae. Disease-specific clinical
Juliette Brenner   +5 more
openaire   +2 more sources

Assessment of sexual difficulties associated with multi-modal treatment for cervical or endometrial cancer: A systematic review of measurement instruments [PDF]

open access: yes, 2016
Background: Practitioners and researchers require an outcome measure that accurately identifies the range of common treatment-induced changes in sexual function and well-being experienced by women after cervical or endometrial cancer.
Lucas, G.   +3 more
core   +1 more source

An Assessment of Hand Erosive Osteoarthritis: Correlation of Radiographic Severity with Clinical, Functional and Laboratory Findings

open access: yesRheumatology and Therapy, 2019
Introduction The present study aimed (a) to evaluate the clinical and radiographic characteristics of hand erosive osteoarthritis (EOA) in a group of consecutive patients, (b) to correlate the severity of radiographic involvement with clinical and ...
Fabio Massimo Perrotta   +3 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Establishing meaningful change thresholds for European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire CLL‐specific module domain scores: An analysis based on the TRANSCEND CLL 004 study in patients with relapsed or refractory chronic lymphocytic leukaemia or small lymphocytic lymphoma

open access: yeseJHaem
Introduction The study aimed to establish meaningful thresholds at patient and group levels for the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire CLL‐specific module (EORTC QLQ‐CLL17) domain scores in adults ...
Laurie Eliason   +4 more
doaj   +1 more source

Initial Patient Assessment Workshop

open access: yesMedEdPORTAL, 2010
Introduction In a small-group workshop setting, medical students work with a clinical facilitator on eight basic clinical scenarios. The intention is to guide learners through how they would approach initial assessment of a patient and to help them begin
John Mahoney
doaj   +1 more source

Outcomes in intervention research on snakebite envenomation: a systematic review [version 1; peer review: 2 approved]

open access: yesF1000Research, 2022
Introduction: A core outcome set (COS) is a minimal list of consensus outcomes that should be used in all intervention research in a specific domain. COS enhance the ability to undertake meaningful comparisons and to understand the benefits or harms of ...
Jyoti Tyagi   +6 more
doaj   +1 more source

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