Results 101 to 110 of about 3,006,996 (198)

Integrated Hemodynamic Measures of Cardiac Function and Association With Clinical Outcomes. [PDF]

JACC Adv
Trad OK, Parekh JK, Kosyakovsky LB, Mounsey L, Pomerantsev EV, Picard MH, Quintero Pinzon PA, Sabe M, Grandin EW, Garan AR, Ho JE.   +10 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Cigarette smoking exposure and clinical outcomes in Graves' disease.

J Clin Endocrinol Metab
Forbes S, Loo M, Tee SA, Stewart K, Vernazza J, Carroll L, Vennart N, Bartholomew P, Narayanan K, Tsatlidis V, Razvi S.   +10 more
europepmc   +1 more source

Impact of Concomitant Mitral Regurgitation in Moderate Aortic Stenosis: Assessment of Remodeling and Clinical Outcomes. [PDF]

JACC Cardiovasc Imaging
Gabr EM, Xiao M, Saeed M, Darwish A, Bersali A, Dhore-Patil A, Songsangjinda T, Graviss EA, Kleiman NS, Malahfji M, Shah DJ.   +10 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Clinical outcomes of non-traumatic chylothorax at a Singapore tertiary referral hospital. [PDF]

BMJ Open Respir Res
Chua BLW, Young SL, Tan QL, Leong CK, Wong JJY, Phua IGCS, Lim WT, Goh KJ.   +7 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Publishing anaesthetists' clinical outcomes [PDF]

Anaesthesia, 2016
openaire   +2 more sources

Recent advances in Mpox across innate immunity, evasion, and clinical outcomes. [PDF]

Commun Biol
Oh J, Chung YS, Lee S.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source