Results 241 to 250 of about 5,379,197 (286)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The role of estrogen in cardiac transplantation: mechanistic insights and effects on clinical outcomes. [PDF]

Front Transplant
Wolff von Gudenberg R, Kupsch C, Gilles L, Xiao Y, Ortiz-Koh C, Ruhparwar A, Zhou H, Tullius SG.   +7 more
europepmc   +1 more source

Prenatal ultrasound diagnosis of fetal cardiac rhabdomyoma and analysis of clinical outcomes. [PDF]

Quant Imaging Med Surg
Zhao J, Jia P, Zhang Q, Li T, Ma B, Yan Z.   +5 more
europepmc   +1 more source