Results 51 to 60 of about 5,451,020 (208)

Group sequential designs for negative binomial outcomes

open access: yes, 2018
Count data and recurrent events in clinical trials, such as the number of lesions in magnetic resonance imaging in multiple sclerosis, the number of relapses in multiple sclerosis, the number of hospitalizations in heart failure, and the number of ...
Friede, Tim   +3 more
core   +1 more source

Cutaneous Manifestations in Patients with Dermatomyositis, Are They Only Skin Deep?

open access: yesDermatology and Therapy
Background Dermatomyositis (DM) is a rare and severely debilitating autoimmune disease that can affect children and adults; however, there is little understanding of the patient-reported experience and uncertainty around validated clinical outcomes ...
Stephanie McKee   +6 more
doaj   +1 more source

Survival outcomes in men with a positive family history of prostate cancer: a registry based study

open access: yesBMC Cancer, 2020
Background To investigate the correlation between family history of prostate cancer (PCa) and survival (overall and cancer specific) in patients undergoing treatment for PCa.
Mann Ang   +3 more
doaj   +1 more source

Proceedings of the 2021 Cannabis Clinical Outcomes Research Conference

open access: yesMedical Cannabis and Cannabinoids, 2021
The Cannabis Clinical Outcomes Research Conference (CCORC) 2021 was held virtually on April 8 and 9, 2021. The conference was hosted by the Consortium for Medical Marijuana Clinical Outcomes Research, a research organization instituted by the state ...
Amie J. Goodin   +5 more
doaj   +1 more source

Postoperative low dose CT assessment of interbody fusion two years after thoracoscopic scoliosis surgery [PDF]

open access: yes, 2011
The relationship between radiologic union and clinical outcomes in thoracoscopic scoliosis surgery is not clear, as apparent non-union of a spinal fusion does not always correspond to a poor clinical result.
Adam, Clayton   +4 more
core   +1 more source

Disparities in COVID-19 hospitalizations and mortality among black and Hispanic patients: cross-sectional analysis from the greater Houston metropolitan area

open access: yesBMC Public Health, 2021
Background Disparate racial/ethnic burdens of the Coronavirus Disease 2019 (COVID-19) pandemic may be attributable to higher susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) or to factors such as differences in ...
Alan P. Pan   +9 more
doaj   +1 more source

Exit interviews with caregivers of pediatric patients with classic galactosemia to explore meaningfulness of changes in the ACTION-galactosemia kids trial

open access: yesOrphanet Journal of Rare Diseases
Background Classic Galactosemia is a rare, autosomal recessive disease in which galactose is not metabolized properly due to severe deficiency/absence of the galactose-1-phosphate uridylyltransferase (GALT) enzyme, converting to an aberrant and toxic ...
Jason A. Randall   +7 more
doaj   +1 more source

Exploring content and psychometric validity of newly developed assessment tools for itch and skin pain in atopic dermatitis

open access: yesJournal of Patient-Reported Outcomes, 2019
Background Atopic dermatitis (AD) is a common skin disorder characterized by chronic inflammation, altered skin barrier function, and inflammatory cell skin infiltration that decreases health-related quality of life (HRQoL).
Louise Newton   +11 more
doaj   +1 more source

Committee experiences of using formal consensus in healthcare guidelines: a longitudinal qualitative study

open access: yesBMC Medical Informatics and Decision Making, 2023
Background This feasibility study has the primary aim of capturing and comparing participant expectations and experiences of using a formal consensus method (FCM) and to explore whether these views change following participation within a guideline ...
V Roberts   +4 more
doaj   +1 more source

Association of Chorioamnionitis with Aberrant Neonatal Gut Colonization and Adverse Clinical Outcomes. [PDF]

open access: yes, 2016
ObjectiveChorioamnionitis (inflammation of the placenta and fetal membranes) and abnormal gastrointestinal colonization have been associated with an increased risk of sepsis and death in preterm infants, but whether chorioamnionitis causes abnormal ...
Ambalavanan, Namasivayam   +5 more
core   +1 more source

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