Results 81 to 90 of about 5,794,890 (214)

PathBeat. Number 14 (Winter 2013) University of Iowa Department of Pathology. [PDF]

, 2013
University of Iowa Department of Pathology ...

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Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Challenging the Clinical Paradigm of Hepatozoon canis: A Primary Pathogen Causing Clinically Significant Disease at Low Parasitaemia and a Chronic Inflammatory State

Veterinary Medicine and Science
Background Hepatozoon canis is an important canine pathogen transmitted by the brown dog tick, Rhipicephalus sanguineus, causing a vector‐borne disease with variable clinical severity.
Somayeh Bahrami, Zahra Mashayekhi, Seyedeh Misagh Jalali, Mohammad Khosravi, Mohammad Rajabloo   +4 more
doaj   +1 more source

Usefulness of cerebrospinal fluid analysis in dogs and cats with suspected intracranial disease and normal magnetic resonance imaging

Frontiers in Veterinary Science
Cerebrospinal fluid (CSF) analysis is a common diagnostic tool in the investigation of neurological presentations. Whether its routine use after every brain magnetic resonance imaging (MRI) is warranted is debated amongst clinicians, and its usefulness ...
Susana R. Monforte Monteiro, Luisa De Risio, Lisa Alves, An E. Vanhaesebrouck   +3 more
doaj   +1 more source

Natural language processing in pathology: a scoping review

, 2016
Background Encoded pathology data are key for medical registries and analyses, but pathology information is often expressed as free text. Objective We reviewed and assessed the use of NLP (natural language processing) for encoding pathology documents ...
Abu-Hanna, Ameen,, Burger, Gerard, Cornet, Ronald, Burger, Gerard,, Abu-Hanna, Ameen, de Keizer, Nicolette, de Keizer, Nicolette,, Cornet, Ronald,   +7 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Beyond Individual Acute Phase Protein Assessments: Introducing the Acute Phase Index (API) as a Prognostic Indicator in Dogs with Malignant Neoplasia

Veterinary Sciences
Acute phase proteins (APPs) are part of the innate immune response, changing during inflammation. An Acute Phase Index (API) is a calculated value that combines multiple APPs.
Martina Baldin, Maria Elena Gelain, Giacomo Marolato, Silvia Bedin, Michele Berlanda, Manuela Zanetti, Filippo Torrigiani, Alessia Giordano, Pierangelo Moretti, Donatella Scavone, Federico Bonsembiante   +10 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Construction of nomogram model of poor prognosis for patients newly diagnosed with brain metastasis from non-small cell lung cancer based on clinical pathology and prognostic scores

Frontiers in Oncology
ObjectiveTo explore non-small cell lung cancer (NSCLC) patients with new diagnosis of brain metastasis and construct Logistic regression model based on clinical pathology and prognosis score, and verify.MethodsA total of 158 patients newly diagnosed with
Zengliang Li, Zengliang Li, Xiaoyue Wang, Xiaoyue Wang, Guodong Ma, Guodong Ma   +5 more
doaj   +1 more source

Handling and reporting of radical prostatectomy specimens: A practice survey

, 2006
Annual Meeting of the American-Society-for-Clinical-Pathology -- OCT 19-22, 2006 -- Los Angeles, NVAmer Soc Clin ...
Doganavsargil, Basak, Hekimgil, Mine, Nalbantoglu, Ilke   +2 more
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