Results 81 to 90 of about 1,686,489 (300)

Beyond Individual Acute Phase Protein Assessments: Introducing the Acute Phase Index (API) as a Prognostic Indicator in Dogs with Malignant Neoplasia

Veterinary Sciences
Acute phase proteins (APPs) are part of the innate immune response, changing during inflammation. An Acute Phase Index (API) is a calculated value that combines multiple APPs.
Martina Baldin, Maria Elena Gelain, Giacomo Marolato, Silvia Bedin, Michele Berlanda, Manuela Zanetti, Filippo Torrigiani, Alessia Giordano, Pierangelo Moretti, Donatella Scavone, Federico Bonsembiante   +10 more
doaj   +1 more source

Natural language processing in pathology: a scoping review

, 2016
Background Encoded pathology data are key for medical registries and analyses, but pathology information is often expressed as free text. Objective We reviewed and assessed the use of NLP (natural language processing) for encoding pathology documents ...
Abu-Hanna, Ameen,, Burger, Gerard, Cornet, Ronald, Burger, Gerard,, Abu-Hanna, Ameen, de Keizer, Nicolette, de Keizer, Nicolette,, Cornet, Ronald,   +7 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Nevus-Associated Melanomas: Clinicopathologic Features

, 2014
Objectives: the clinical significance of nevus-associated melanoma compared with de novo melanomas remains controversial. It has been suggested that nevus-associated melanomas have a higher Breslow thickness and therefore worse prognosis.
Yamada, Sergio [UNIFESP], Bagatin, Edileia [UNIFESP], Enokihara, Milvia M. S. S. [UNIFESP], Michalany, Nilceo [UNIFESP], Shitara, Danielle [UNIFESP], Nascimento, Mauricio M. [UNIFESP], Puig, Susana   +6 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Clinical and pathological observation of conversion therapy for malignant peritoneal mesothelioma: a case report and literature review

Pathology and Oncology Research
Background: Malignant mesothelioma (MM) is a tumor originating from the pleura, peritoneum, or pericardial cavity. It is divided into diffuse and localized malignant mesothelioma, with four subtypes in diffuse MM: epithelioid, sarcomatoid, desmoplastic ...
Minying Deng, Xinyi Zhang, Chen Xu, Rongkui Luo, Lingli Chen, Yuhong Zhou, Yingyong Hou   +6 more
doaj   +1 more source

The ethical challenges of artificial intelligence‐driven digital pathology

, 2022
Digital pathology – the digitalisation of clinical histopathology services through the scanning and storage of pathology slides – has opened up new possibilities for health care in recent years, particularly in the opportunities it brings for artificial ...
Williams, Bethany J.,, Bansal, Daljeet, Treanor, Darren,, Williams, Bethany J, Hallowell, Nina, Darren Treanor, Prestwich, Graham,, McKay, Francis, Prestwich, Graham, Francis McKay, Bansal, Daljeet,, McKay, Francis,, Daljeet Bansal, Williams, Bethany J., Graham Prestwich, Treanor, Darren, Bethany J Williams, Hallowell, Nina,, Nina Hallowell   +18 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

How can the postgraduate training program in pathology departments in India be improved?

Indian Journal of Pathology and Microbiology, 2011
There exists a wide variation in the competence of the postgraduate residents trained in pathology in different institutions across India. This results in strong disparities in the clinical diagnostic skills, teaching skills, research capabilities and ...
Shivayogi R Bhusnurmath, Bharti S Bhusnurmath   +1 more
doaj   +1 more source

Handling and reporting of radical prostatectomy specimens: A practice survey

, 2006
Annual Meeting of the American-Society-for-Clinical-Pathology -- OCT 19-22, 2006 -- Los Angeles, NVAmer Soc Clin ...
Doganavsargil, Basak, Hekimgil, Mine, Nalbantoglu, Ilke   +2 more
core