Results 61 to 70 of about 1,695,081 (360)

The Liverpool Care Pathway [PDF]

open access: yes, 2013
For many practising doctors, especially in general practice or in general internal medicine, decisions at the end of life are often some of the most difficult.
Saunders, John
core  

Clinical Experience With Hedgehog Pathway Inhibitors

open access: yes, 2010
The Hedgehog (Hh) signaling pathway is critical for cell growth and differentiation during embryogenesis and early development. While it is mostly quiescent in adults, inappropriate reactivation of the Hh pathway has been shown to be involved in the ...
Jennifer A. Low, Frederic J. de Sauvage
core   +1 more source

Post-discharge “continuum of care” clinical pathway (CP) for persons with severe neuro-disabilities – qualitative research to model needs-based community healthcare, capture the real-life care situation, and assess the appropriateness of the CP's concept with input from community- and hospital-based healthcare professionals

open access: yesFrontiers in Neurology
ObjectiveTo document opinions and experiences of representatives from three different interest groups regarding “needs-based healthcare” of people with severe neuro-disability requiring home-based specialized intensive care nursing (HSICN) and continued ...
Stephanie Reichl   +11 more
doaj   +1 more source

Establishing A Clinical Pathway For Adult Intubated Patients To Prevent Post-Extubation Complications. [PDF]

open access: yesAlexandria Scientific Nursing Journal
Background: An endotracheal tube (ETT) is one of the essential artificial airways that is used forrespiratory support for critically ill patients. However, the presence of ETT is associated with variousfatal complications which diagnosed mainly in post ...
Azza Hamdi El-soussi,   +4 more
doaj   +1 more source

Impact of clinical pathways in surgery [PDF]

open access: yesLangenbeck's Archives of Surgery, 2008
BACKGROUND: One strategy to reduce the consumption of resources associated to specific procedures is to utilize clinical pathways, in which surgical care is standardized and preset by determination of perioperative in-hospital processes. The aim of this prospective study was to establish the impact of clinical pathways on costs, complication rates, and
Müller, M K   +5 more
openaire   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Measuring Perceptions of the Clinical Career Pathway in a New Zealand Hospital [PDF]

open access: yes, 2002
Clinical Career Pathways (CCPs) for nurses were introduced in the 1970s and they were first established in New Zealand during the late 1980s. The implementation of CCP programmes has met with mixed response; many nurses view it negatively as an extra and
Anne Russell   +2 more
core  

A Pathway Analysis Tool for Analyzing Microarray Data of Species with Low Physiological Information [PDF]

open access: yes, 2008
Pathway information provides insight into the biological processes underlying microarray data. Pathway information is widely available for humans and laboratory animals in databases through the internet, but less for other species, for example, livestock.
Pas, M.F.W., te   +13 more
core   +1 more source

Reducing clinical variations with clinical pathways: do pathways work? [PDF]

open access: yesInternational Journal for Quality in Health Care, 2003
To test clinical pathways in a variety of Italian health care organizations in 2000-2002 to measure performance in decreasing process and outcome variations.Creation of indicators, specific for each clinical pathway, to measure variations in the care processes and outcomes.
PANELLA, Massimiliano   +2 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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