Retracted: Effect Analysis of Clinical Pathway Nursing Combined with Humanized Nursing in Cerebral Infarction [PDF]
, 2023 Computational Intelligence and Neuroscience
openalex +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2011 Mammalian target of rapamycin (mTOR) is a PI3K-related kinase that regulates cell growth, proliferation, and survival via mTOR complex 1 (mTORC1) and mTORC2. The mTOR pathway is often aberrantly activated in cancers.
Slingerland, Joyce M +5 more
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Clinical Value of SARS-CoV2 IgM and IgG Antibodies in Diagnosis of COVID-19 in Suspected Cases
Journal of Inflammation Research, 2020 Yangchun Feng Clinical Laboratory Center, The Third Hospital Affiliated to Xinjiang Medical University (Affiliated Cancer Hospital), Urumqi, 830011, People’s Republic of ChinaCorrespondence: Yangchun FengThird Hospital Affiliated to Xinjiang ...
Feng Y
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An audit to determine the clinical effectiveness of a pathway for managing wound infection
, 2015 Prevention of wound infection is a key objective in the planning of care for patients with wounds. The potential for wound infection, particularly in chronic wounds that are heavily contaminated with bacteria, can be high (Bowler et al, 2001).
Stephenson, John, Grothier, Lorraine
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Phosphorylation of the androgen receptor is associated with reduced survival in hormonerefractory prostate cancer patients [PDF]
, 2008 Cell line studies demonstrate that the PI3K/Akt pathway is upregulated in hormone-refractory prostate cancer (HRPC) and can result in phosphorylation of the androgen receptor (AR).
L K Gemmell +9 more
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Municipal Acute Units as Part of the Clinical Pathway for Older Patients
International Journal of Integrated Care, 2019 Introduction: Since 2016, Norwegian municipalities have been obliged to provide municipal acute 24-hour services representing a service before or instead of hospital treatment.
Anne-Kari Johannessen, Sissel Steihaug
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Evaluation of the effectiveness of a clinical pathway for bronchiolitis
, 2005 Objective: This study examines the use of a clinical pathway in the management of infants hospitalised with bronchiolitis. Study Design: A clinical pathway for the care of infants with bronchiolitis was developed from pathways used in tertiary ...
Cheney, Joyce Louise
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