Results 91 to 100 of about 1,695,081 (360)

Reducing physician voiding cystourethrogram ordering in children with first febrile urinary tract infection: evaluation of a purposefully sequenced educational intervention

Canadian Medical Education Journal, 2018
Background: Physicians often fail to implement clinical practice guidelines. Our aim was to evaluate whether a purposefully sequenced, multifaceted educational intervention would increase physician adherence to a guideline for voiding cystourethrogram ...
Anke Banks, Susan Samuel, David Johnson, Kent Hecker, Kevin McLaughlin   +4 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Application effect of clinical pathway in exchange transfusion therapy for neonatal ABO hemolytic disease

Huli yanjiu, 2016
Objective:To probe into the application effect of clinical pathway in neonatal ABO exchange transfusion therapy for hemolytic disease.Methods:The beforeafter control design was used,a total of 176 with ABO hemolytic disease after clinical pathway ...
杨丽莎, 何华云, 陈新红, 鞠燕
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Clinical academic career pathway for nursing and allied health professionals: clinical academic role descriptors

, 2011
The clinical academic pathway outlined highlights the range of typical practice and research-focused activities that a practitioner on a clinical academic career pathway might normally engage in at different levels and points along this career path.
Fader, M., Coombs, M.A., Duke, Sue, Rankin, Suzanne, Westbury, Jan, Kitsell, Fleur, Atherton, Lesley, Lewis, Adam, Bailey, Christopher, Chable, Rosemary, Stephenson, Jan, Green, Sue, Latter, S., Diggins, Jude, Prieto, Jacqui, Richardson, Alison   +15 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A clinical pathway for bronchiolitis is effective in reducing readmission rates

, 2005
Objective To examine the use of a clinical pathway in the management of infants hospitalized with acute viral ...
Barber, Scott, Cheney, Joyce, Yates, Patsy, O'Rourke, Peter, Cheney, Joyce L., Altamirano,Luis, Cheney, Marise, Williams, Chris, Altamirano, Luis, Medico-Cirujano, Marise, Wainwright, Claire, Jackson, Mary   +11 more
core   +1 more source

DRG付费方式和临床路径管理对脑梗死患者住院费用影响的联合作用分析 Analysis of the Combined Effect of DRG Payment and Clinical Pathway Management on the Hospitalization Cost of Patients with Cerebral Infarction

Zhongguo cuzhong zazhi
目的 探讨疾病诊断相关分组（diagnosis related groups，DRG）付费制度和临床路径管理对脑梗死患者住院费用的控制效果及其联合作用。 方法 选取安徽省某三级甲等医院2022年11月1日—2023年10月31日出院主诊断为脑梗死的住院患者为研究对象，结合病案首页及合肥市医保中心医疗保障信息系统反馈，将患者分为非DRG结算非临床路径组、只采取DRG结算组、只纳入临床路径组、DRG结算联合临床路径组，采用单因素分析探讨不同组别患者的基线特征及费用差异。调整年龄、性别、入院途径 ...
王玲玲1，王晓楠1，王真明1，周道平2，张现格3，王文君1 (WANG Lingling1, WANG Xiaonan1, WANG Zhenming1, ZHOU Daoping2, ZHANG Xian’ge3, WANG Wenjun1 )
doaj   +1 more source

Adverse Childhood Experiences and Mental Health in Women: Pathways of Influence in a Clinical Sample

, 2021
Yolanda Fontanil Gómez, María L. Méndez, Yolanda Martín-Higarza, Patricia Solís García, Esteban Ezama   +4 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source