Results 111 to 120 of about 1,695,081 (360)

Characteristics of Late-onset Asthma in Elderly Asthmatic Patients

Allergology International, 2005
Background: We evaluated the characteristics of late-onset asthma in elderly patients with asthma, particularly concerning the relationship of IgE mediation and response to treatment. Methods: This study included asthma patients aged 60 or older who were
Hirotaka Yasuba, Yoshiki Kobayashi, Megumi Kudou, Kazuyuki Hamada, Hideo Kita   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Clinical pathway variance prediction using artificial neural network for acute decompensated heart failure clinical pathway [PDF]

, 2018
Patients in modern healthcare demand superior healthcare quality. Clinical pathways are introduced as the main tools to manage this quality. A clinical pathway is a task-oriented care plan that specifies steps to be taken for patient care. It follows the
Mohd. Zahid, Mohd. Soperi, Haron, Habibollah, Satria, Muhammad Haikal, Abd. Ghazi, Azmee, Talib, Mohamad Shukor, Abu Yazid, Mohamad Haider   +5 more
core   +1 more source

Strategy to Identify Infants with Hypoxic Ischemic Encephalopathy for Therapeutic Hypothermia—A Retrospective Audit

Children
Background/Objectives: Although there is a critical need for timely, accurate recognition of infants with hypoxic ischemic encephalopathy (HIE) eligible for therapeutic hypothermia (TH), there is little published literature that comprehensively validates
Kristen Haakons, Kaycee Hocking, Richard Mausling, Helen G. Liley   +3 more
doaj   +1 more source

Research on the development and management of clinical pathways Ⅲ: thoughts on the work of clinical pathways under the DRG/DIP payment model of medical insurance payment [PDF]

Yixue xinzhi zazhi
China is actively promoting Diagnosis-Related Group (DRG)/Diagnosis-Intervention Packet (DIP) payment reform alongside the implementation of clinical pathways.
PENG Shuzhen, LOU Jia'ao, LIN Kewen, YI Ye, JIN Yinghui, FENG Jiajia, ZHANG Pan, LIN  Likai, ZENG Hongli   +8 more
doaj   +1 more source

A liability checklist for clinical pathways

Nursing Management (Springhouse), 2002
To ensure safe, responsible use of clinical pathways, follow written policies and procedures and document all patient care.
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Differential effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway in acute lymphoblastic leukemia

, 2013
Purpose: Aberrant PI3K/AKT/mTOR signaling has been linked to oncogenesis and therapy resistance in various malignancies including leukemias. In Philadelphia chromosome (Ph) positive leukemias, activation of PI3K by dysregulated BCR-ABL tyrosine kinase ...
Oliver G Ottmann, Martin Ruthardt, Oliver G. Ottmann, Oliver G. Ottmann (485229), Falkenburg, J.H.F., Marcus Liebermann (485228), Bart A. Nijmeijer (485227), Pfeifer, Heike, Falkenburg, J. H. Frederik, J. H. Frederik Falkenburg, Ruthardt, Martin, Tamara Tesanovic, Tesanovic, Tamara, Bart A Nijmeijer, Heike Pfeifer, Ottmann, Oliver G., Susanne Badura (485223), Sylvia Wystub, Sylvia Wystub (485226), Liebermann, M., Marcus Liebermann, Bart A. Nijmeijer, Ottmann, O.G., Nijmeijer, Bart A., Badura, S., Susanne Badura, Wystub, Sylvia, Pfeifer, H., J H Frederik Falkenburg, Tamara Tesanovic (485224), Martin Ruthardt (66634), Wystub, S., Nijmeijer, B.A., Ruthardt, M., Tesanovic, T., Badura, Susanne, Heike Pfeifer (485225), J. H. Frederik Falkenburg (210432), Liebermann, Marcus   +38 more
core   +1 more source

Expanding the Hippo pathway : hMOB3 modulates apoptotic MST1 signaling and supports tumor growth in glioblastoma [PDF]

, 2014
Protein kinases are critical players of signal transduction pathways involved in development, physiological and pathological processes. Deregulation of protein kinase signaling is found to be causal or related to varieties of human diseases, such as ...
Tang, Fengyuan
core   +1 more source

Research on the development and management of clinical pathways Ⅰ: theories, methods, processes and suggestions for clinical pathways development [PDF]

Yixue xinzhi zazhi
The formulation and application of clinical pathways is a process of dynamic improvement and development. The principles of clinical pathways formulation come from multiple disciplines and are constantly enriched and polished in the clinical application ...
YI Ye, LIN Kewen, LOU Jiaao, PENG Shuzhen, JIN Yinghui, FENG Jiajia, ZHANG Pan, LIN Likai, WANG Xinghuan   +8 more
doaj   +1 more source