The fanconi anemia DNA repair pathway is regulated by an interaction between ubiquitin and the E2-like fold domain of FANCL [PDF]
The Fanconi Anemia (FA) DNA repair pathway is essential for the recognition and repair of DNA interstrand crosslinks (ICL). Inefficient repair of these ICL can lead to leukemia and bone marrow failure.
Howard, Mark J. +8 more
core +1 more source
Analisa Biaya Pengobatan Demam Tifoid Berdasarkan Clinical Pathway Di Rumah Sakit Harapan Bunda
Clinical pathways are used in quality and cost control with indicators of length of stay. Cases of typhoid fever at Harapan Bunda Hospital include the criteria for the first rank of High Volume in 2018 and Problem Prone in the cost of treatment.
Pieter Hazmen +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Exploring the developmental need for a paramedic pathway to mental health
The following article discusses an organisational development need of a national 'Mental Health Pathway' to enable paramedics to provide the appropriate care for people who present mental health issues.
Elliott, Ruth
core
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
The remodelling of patient care pathway for e-health
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The interdependencies within the health care system are seldom taken into account prior to implementation of e-health projects, and there tends to be little
Jones, Karen
core
Kate Curtis,1– 4 Peter Moules,2 John McKenzie,2,3 Lauren Weidl,2 Tanya Selak,2 Simon Binks,2 Daniel Hernandez,2 Joshua Rijsdijk,2 Dante Risi,2 James Wright,5 Lauren O’Rourke,2 Myles Knapman,6 Meagan Ristevski,2 Teala Stephens,2 Ian Harris,7 ...
Curtis K +15 more
doaj
Effect of the use of Clinical Pathway for Patients with Unstable Angina on Nursing Performance and Patient's Outcomes [PDF]
Zienab Ibrahim
openalex +1 more source
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy [PDF]
Jiayue Qiu +7 more
openalex +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source

