Results 211 to 220 of about 1,543,622 (248)

Outcomes of newly referred patients with suspected angle closure: do we need to redefine the clinical pathways? [PDF]

Eye (Lond)
Founti P, Narayan A, Raja A, Nathwani N, Tur SB, Thomas R, Scott A, Martins A, Nolan W.   +8 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Identifying Key Variances in Clinical Pathways Associated With Prolonged Hospital Stays Using Machine Learning and ePath Real-World Data: Model Development and Validation Study.

JMIR Med Inform
Tou S, Matsumoto K, Hashinokuchi A, Kinoshita F, Nohara Y, Yamashita T, Wakata Y, Takenaka T, Soejima H, Yoshizumi T, Nakashima N, Kamouchi M.   +11 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Supplementary Figure 1 from Molecular Pathways and Cellular Subsets Associated with Adverse Clinical Outcomes in Overlapping Immune-Related Myocarditis and Myositis

Bilal A. Siddiqui, Nicolas L. Palaskas, Sreyashi Basu, Yibo Dai, Zhong He, Shalini S. Yadav, James P. Allison, Rahul A. Sheth, Sudhakar Tummala, L. Maximilian Buja, Meenakshi B. Bhattacharjee, Cezar Iliescu, Anishia Rawther-Karedath, Anita Deswal, Linghua Wang, Padmanee Sharma, Sumit K. Subudhi   +16 more
openalex   +1 more source

Clinical Course, Laboratory Findings, and Prognosis of SARS-CoV-2 Infection in Infants up to 90 Days of Age: A Single-Center Experience and a Proposal for a Management Pathway [PDF]

Tommaso Bellini, Giacomo Brisca, Ioannis Orfanos, Marcello Mariani, Federico Pezzotta, Benedetta Giordano, Andrea Pastorino, Silvia Misley, Clelia Formigoni, Elena Fueri, Marta Ferretti, Marta Marin, Martina Finetti, Emanuela Piccotti, Elio Castagnola, Andrea Moscatelli   +15 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Early surgical treatment using regional clinical pathways to reduce the length of postoperative hospital stay in hip fracture patients: A retrospective analysis using the Japanese Diagnosis Procedure Combination database. [PDF]

PLoS One
Nishimura H, Suzuki H, Tokutsu K, Muramatsu K, Kawasaki M, Yamanaka Y, Uchida S, Nakamura E, Fushimi K, Matsuda S, Sakai A.   +10 more
europepmc   +1 more source