Results 91 to 100 of about 5,794,212 (304)
, 2018 Antonio Olea Jr,1 Janet Grochowski,1 Anne F Luetkemeyer,1 Valerie Robb,1 Parya Saberi2 1Division of HIV, Infectious Diseases and Global Medicine, Zuckerberg San Francisco General, San Francisco, CA, USA; 2Department of Medicine, School of Medicine ...
Robb V +4 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Medicine Science, 2016 Diabetes mellitus is a chronic disorder characterized by hyperglycemia andthe late development of vascular and neuropathic complications. Diabetes is best managed by multidisciplinary care team and overlapping skills: physician, specialist diabetes nurse,
Hashem Mohammed Mansour
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Clinical Pharmacists in Chronic Care
Global Journal of Medical Research, 2019 Pharmacy practice has changed significantly lately. The professionals have the chance to contribute straightforwardly to patient consideration so as to lessen morbimortality identified with medication use, promoting wellbeing and preventing diseases.
openaire +2 more sources
Huge colo-mezenteric cystic lympgangioma: A case report
Medicine Science, 2018 A 29-year old female patient was presented to the our department with mild intermittent lower abdominal pain. Otherwise she was healthy and she did not report previous exposure to toxic chemical agents.
Hashem Mansour +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
International Journal of Hematology-Oncology and Stem Cell Research, 2010 Introduction: The aim of this study was to evaluate the use of albumin in bone marrow transplanted patients and its possible economic repercussions from its inappropriate use.
Maryam Mousavi Nejad +8 more
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Suicide risk identification and mitigation in patients with chronic pain prescribed opioid medication [PDF]
Mental Health ClinicianManaging suicidality in persons with chronic pain is a challenging clinical scenario with no treatment guidelines to inform clinical decision-making related to suicide risk mitigation.
Dana L. Chiulli, PharmD, BCPP
doaj +1 more source