Results 81 to 90 of about 5,794,212 (304)

Clinical impact of a pharmacist-led inpatient anticoagulation service: a review of the literature

, 2016
Tiffany Lee, Erin Davis, Jason Kielly School of Pharmacy, Memorial University, St John's, NL, Canada Background: Anticoagulant therapies provide management options for potentially life-threatening thromboembolic conditions.
Davis E, Kielly J, Lee T
core  

Pharmacist administration of long-acting injectable medications for substance use disorders: A scoping review [PDF]

Mental Health Clinician
Introduction: Using long-acting injectable (LAI) medications increases treatment adherence and promotes positive outcomes for patients with substance use disorders (SUD).
Pamela Hernandez Bustamante, BS, PharmD, Amanda Charles, PharmD, BCPS, Marissa Snider, PharmD, MPH, Samantha Catanzano, PharmD, BCPP   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Pharmacist-led medicines optimisation service in an inpatient mental health setting

Medicines optimisation ensures that people get the best possible outcomes from their medicines. As those with severe mental illness (SMI) are frequently prescribed psychotropic medicines with potentially significant side-effects, poor adherence to ...
Georgina Gilsenan (17815390), Caroline Hynes-Ryan (17815315), Dolores Keating (7896611), Larkin Feeney (7955888), Audrey Purcell (12596449), Aoife Carolan (7896860), Judith Strawbridge (7897367), Darragh O'Donoghue (17815392)   +7 more
core   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Clinical, Economic, and Organizational Impact of the Clinical Pharmacist in an Orthopedic and Trauma Surgery Department

, 2018
International audienceThe aim of this study was to evaluate the clinical, economic, and organizational impact of clinical pharmacist services added to an adult orthopedic and trauma surgery unit in a university ...
Jalabert, Anne, Breuker, Cyril, Audurier, Yohan, Dagneaux, Louis, Renaudin, Pierre, Villiet, Maxime, Canovas, François, Coste, Annabelle, Castet-Nicolas, Audrey, Berbis, Julie, Mercier, Grégoire   +10 more
core   +1 more source

Evaluating patient perceived effectiveness, safety, and satisfaction with a pharmacist-led clinical wound care serviceKey Points

JAPhA Practice Innovations
Background: Chronic wounds are associated with morbidity, reduced quality of life, and high healthcare costs. Topical antibiotics offer localized therapy, and community pharmacists can support patients through individualized therapy, education, and ...
Victoria Pinkovsky, Traci Poole, Angela Hagan   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Activities of the Clinical Pharmacist Practicing in the Office of a Family Practitioner

, 1975
The activities of a clinical pharmacist within a primary care facility are measured in a time-motion study. This type of practice allows the pharmacist an opportunity to provide many patient-care services normally unavailable at community pharmacies. The
Stephen C. Hurley, Paul J. Perry
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source