Opportunities and Challenges of Using Big Data to Detect Drug-Drug Interaction Risk [PDF]
Chasioti D. +1 more
core +1 more source
Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain
ABSTRACT In this study, we analyzed biomarkers of neuronal, glial, and vascular injury in longitudinal paired samples of blood and cerebrospinal fluid after prophylactic cranial irradiation in patients with small cell lung cancer. Neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAP) increased in serum and cerebrospinal ...
Erik Fernström +5 more
wiley +1 more source
Clinical Pharmacology Perspective on Direct-To-Subcutaneous Dosing of T Cell Engagers in Oncology First-In-Human Studies. [PDF]
Qiao W +3 more
europepmc +1 more source
Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker +9 more
wiley +1 more source
CLINICAL NEUROPHARMACOLOGY.Henn Kutt and Fletcher McDowell, with contributions by H. Masur and H.W. Murray Vol. 4 of Monographs in Clinical Pharmacology, Azarnoff, D.L. (ed.), Churchill Livingstone, New York, Edinburgh, London, 1979. 213 $28.15. [PDF]
Carl Pinsky
openalex +1 more source
Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman +5 more
wiley +1 more source
Predictive AI in Clinical Pharmacology: A Call to Action to Develop Robust Benchmarking Practices. [PDF]
Ponce-Bobadilla AV +13 more
europepmc +1 more source

