Results 241 to 250 of about 9,870,305 (401)

The Finite Absorption Time Concept Guiding Model Informed Drug & Generics Development in Clinical Pharmacology. [PDF]

Pharm Res
Macheras P, Tsekouras AA, Sánchez-Herrero S, Kosmidis K.   +3 more
europepmc   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

Advanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun, Jiachen Lin, Chenyang Xue, Yuyan Wang, Peiru Chen, Yun Wei, Guobin Xu, Anais Sidonia, Chris Nenopoulos, Hossam Tashkandi, Caroline Shen, Allison Wang, Alex Wang, Ke Zhang   +13 more
wiley   +1 more source

Book Review: Drug Treatment: Principles and Practice of Clinical Pharmacology and Therapeutics [PDF]

, 1978
Laurence Després
openalex   +1 more source

Clinical Pharmacology of Asciminib: A Review. [PDF]

Clin Pharmacokinet
Hoch M, Huth F, Manley PW, Loisios-Konstantinidis I, Combes FP, Li YF, Fu Y, Sy SKB, Obourn V, Chakraborty A, Hourcade-Potelleret F.   +10 more
europepmc   +1 more source

Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah, Yu Qin, Mark A. Green, James D. E. T. Wilton‐Ely   +3 more
wiley   +1 more source

Evidence to the Royal Commission on the National Health Service. 1. From the Clinical Pharmacology Section of the British Pharmacological Society. [PDF]

, 1978
AN Nicholson, BM Stone
openalex   +1 more source

Clinical Pharmacology [PDF]

, 2018
和田 努, 小野木 康弘, 恒枝 宏史, 笹岡 利安   +3 more
core   +1 more source

The Edges of Clinical Pharmacology: A Narrative Review on Religious and Sociocultural Influences in Drug Management. [PDF]

Clin Transl Sci
Di Maria S, Provenzani A.
europepmc   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

Clinical Pharmacology of Cefadroxil in Infants and Children

, 1978
Charles M. Ginsburg, George H. McCracken, Joan Clahsen, M. Thomas   +3 more
openalex   +1 more source