Results 311 to 320 of about 9,870,305 (401)

Clinical pharmacology of a new H2 - receptor antagonist, ranitidine (2nd report)

, 1982
Akio Ebihara, Masanobu Tsuru, Kazuoki Kondo, Kyoichi Ohashi, Taichi Oka   +4 more
openalex   +1 more source

Retrospective analysis of diet and gut microbiota diversity and clinical pharmacology outcomes in patients with Parkinsonism syndrome. [PDF]

Heliyon
Hu Y, Wang H, Zhong Y, Sun Y.
europepmc   +1 more source

Liquiritin Exerts a Dual Effect on BMSCs Osteogenic Differentiation and Fracture Healing by Activating the ERK/JNK Pathway and Providing Antioxidant Protection

Advanced Therapeutics, EarlyView.
Liquiritin enhances the osteogenic differentiation of BMSCs and promotes fracture healing through the activation of the ERK/JNK signaling pathway and by exerting antioxidant protective effects. Abstract Liquiritin, a flavonoid from Glycyrrhiza uralensis L., has diverse pharmacological properties, but its impact on fracture healing is unexplored.
Haijun Mao, Jing Liu, Juan Feng, Yalikun Yusufu, Lei Yang, Qing Jiang, Minghui Sun   +6 more
wiley   +1 more source

On placental and lactational transfer of IgG-based therapeutic proteins - Current understanding and knowledge gaps from a clinical pharmacology perspective. [PDF]

Clin Transl Sci
Guinn D, Kratz K, Baisden K, Ridge S, McClymont S, Fletcher EP, Johnson T, Wang YM.   +7 more
europepmc   +1 more source

Automated Transcranial Photobiomodulation in Healthy Rats: Effects on Working Memory and Brain Markers

Advanced Therapeutics, EarlyView.
Transcranial photobiomodulation (PBM) enhances spatial working memory in healthy rats under both continuous and alternating stimulation protocols. At the neural level, PBM modulates cytochrome c oxidase activity, increases prefrontal and hippocampal synaptic markers, and induces region‐specific c‐Fos expression. These effects suggest improved cognitive
Candela Zorzo, Lucía Rodríguez‐Fernández, Emily Gabriela Castillo‐Escalona, Juan A. Martínez, Laura Mañas, Natalia Arias, Jorge L. Arias   +6 more
wiley   +1 more source

An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations. [PDF]

Expert Rev Clin Pharmacol
McCurdy CR, Sharma A, Smith KE, Veltri CA, Weiss ST, White CM, Grundmann O.   +6 more
europepmc   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

A Modified Delphi Study to Establish Essential Clinical Pharmacology Competencies. [PDF]

Ther Innov Regul Sci
Johnson-Williams B, Reynolds K, Gobburu J, Rundio A.   +3 more
europepmc   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source