Results 71 to 80 of about 9,870,305 (401)

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Safe use of meloxicam in clinical practice

open access: yesМедицинский совет, 2019
Non-steroidal anti-inflammatory drugs (NSAIDs) – means of treatment of acute and chronic pain associated primarily with inflammatory changes, so this group of drugs is widely used in neurology, rheumatology, traumatology, etc.
E. I. Sas, V. B. Grinevich
doaj   +1 more source

N-acetylcysteine for non-acetaminophen induced acute liver failure: A review

open access: yesThe Saudi Journal of Gastroenterology, 2022
The use of N-acetylcysteine (NAC) for non-acetaminophen-induced acute liver failure (NAI-ALF) has been increasing despite controversy in its efficacy.
Shirley Xue Jiang   +2 more
doaj   +1 more source

Digital therapeutics and clinical pharmacology

open access: yesTranslational and Clinical Pharmacology, 2019
Digital therapeutics (DTx) is a new subsection of digital health that is primarily driven by software and will be of great interest to clinical pharmacologists.
J. Chung
semanticscholar   +1 more source

Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy. [PDF]

open access: yes, 2020
Intraperitoneal vancomycin is the first-line therapy in the management of peritoneal dialysis (PD)-related peritonitis. However, due to the paucity of data, vancomycin dosing for peritonitis in patients on automated peritoneal dialysis (APD) is empiric ...
Kraft, Walter K.   +6 more
core   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

An on-line solid phase extraction procedure for the routine quantification of caspofungin by liquid chromatography-tandem mass spectrometry [PDF]

open access: yes, 2012
Background: Extensive sets of data are required to investigate the potential use of a therapeutic drug monitoring with individualization of dosage of the antimycotic compound caspofungin.
Kirchhoff, Fabian   +5 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Clinical Pharmacology

open access: yesBritish Journal of Clinical Pharmacology, 2003
P. N. Bennett & M. J. Brown 
Published by Churchill Livingstone, Edinburgh 
ISBN 0‐443‐06480‐6. Price: £39.99.
openaire   +5 more sources

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