Results 81 to 90 of about 9,870,305 (401)

Clinical Pharmacology of Mezlocillin [PDF]

Antimicrobial Agents and Chemotherapy, 1978
Mezlocillin is a new broad-spectrum semisynthetic penicillin that has shown encouraging in vitro activity against the infecting organisms most likely to cause mortality and morbidity in cancer patients receiving chemotherapy. The serum clearances and urine recoveries of mezlocillin, ampicillin, and carbenicillin were compared after the intravenous ...
Susanne S. Weaver, Brian F. Issell, Gerald P. Bodey   +2 more
openaire   +3 more sources

Flipped classroom based on objective structured clinical examinations analysis by undergraduate students of Pharmacology course from the Podiatry Degree improve their learning and assessment communication skills about medicines [PDF]

, 2019
Comunicación cartel con defensa oralWe aim to evaluate the impact of the individual and in-group analysis of OSCEs (filmed by other students) looking for correct and incorrect behaviours and contents in their learning of pharmacology.
Bellido, M Victoria, Bellido-Estevez, Inmaculada, Blanco-Reina, Encarnacion, García-Arnés, Juan Antonio, Gomez-Luque, Jose Aurelio   +4 more
core  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

The clinical pharmacology of obesity [PDF]

Therapeutic Advances in Endocrinology and Metabolism, 2012
With this editorial I would like to introduce myself as a new Associate Editor for Therapeutic Advances in Endocrinology and Metabolism. During my education and academic career I conducted adipose tissue research, and was an investigator in a multitude of obesity studies, either related to weight loss, or treatment of the obese hypertensive patient ...
openaire   +4 more sources

Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies.

Basic & Clinical Pharmacology & Toxicology, 2018
Inconsistencies in the reproducibility of research findings are of pertinent concern throughout the scientific community. Initially addressed in preclinical biomedicine studies [1, 2], the discussion has expanded to fields outside the natural sciences ...
P. Tveden-Nyborg, T. Bergmann, J. Lykkesfeldt   +2 more
semanticscholar   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Impact of Clinical Pharmacological Intervention on Treatment Adherence among Adult Patients with Bronchial Asthma and COPD: A Randomised Clinical Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Adherence to the management of asthma and Chronic Obstructive Pulmonary Disease (COPD) is often suboptimal, which increases morbidity and mortality associated with these chronic respiratory diseases.
Agnik Pal, Santanu Munshi, Santanu K Tripapathi   +2 more
doaj   +1 more source

Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia

Clinical Cancer Research, 2018
Purpose: Tisagenlecleucel is an anti-CD19 chimeric antigen receptor (CAR19) T-cell therapy approved for the treatment of children and young adults with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (B-ALL).
K. Mueller, Edward R. Waldron, S. Grupp, J. Levine, T. Laetsch, M. Pulsipher, M. Boyer, K. August, J. Hamilton, R. Awasthi, A. Stein, D. Sickert, A. Chakraborty, B. Levine, C. June, L. Tomassian, Sweta S. Shah, M. Leung, T. Taran, P. Wood, S. Maude   +20 more
semanticscholar   +1 more source

A framework model for a contextualized and integrated warfarin therapy case in a master of pharmacy program [PDF]

, 2019
© Copyright 2019 American Journal of Pharmaceutical Education.Objective. To develop and integrate a case study on warfarin into a clinical pharmacy workshop. Methods. A framework model was designed and used to create a case study on warfarin therapy. The
Birdi, Amandeep, Fergus, Suzanne, Riaz, Farakh   +2 more
core   +2 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source