Results 81 to 90 of about 798,328 (346)

An integrated general practice and pharmacy-based intervention to promote the use of appropriate preventive medications among individuals at high cardiovascular disease risk: protocol for a cluster randomized controlled trial [PDF]

, 2016
Background: Cardiovascular diseases (CVD) are responsible for significant morbidity, premature mortality, and economic burden. Despite established evidence that supports the use of preventive medications among patients at high CVD risk, treatment gaps ...
Adina Hayek, Anthony Rodgers, Antithrombotic Trialists’ Collaboration, Antithrombotic Trialists’ Collaboration, Anushka Patel, B Mitchell, B Patel, Baldeep Kaur, Bandana Saini, BL Carter, BL Svarstad, BL Svarstad, Blood Pressure Lowering Treatment Trialists' Collaboration, C Armour, C Baigent, Carol Armour, Charlotte Hespe, Christopher Reid, D Peiris, D Peiris, D Peiris, David Peiris, DE Morisky, DE Morisky, DM Wentzlaff, DP Peiris, E Hatah, EL Heeley, Fred Hersch, GF Moore, Ines Krass, JK Lee, KL Margolis, Louise Shiel, M Krousel-Wood, MP Morgado, N Houston Miller, P Ho, R Webster, RB Haynes, RJ Webster, Rohina Joshi, Ruth Webster, S Jan, S Michie, Serigne Lo, Stephen Jan, Tim Usherwood, Tracey-Lea Laba, WK Kellogg Foundation, World Health Organisation   +50 more
core   +4 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Clinical pharmacy practice in developing countries: Focus on India and Pakistan

Archives of Pharmacy Practice, 2014
Clinical pharmacy practice is undergoing unprecedented changes as standard profession of pharmacy practice by means of pharmaceutical care. Although, the clinical pharmacy is well recognized in developed countries, but the implementation of clinical ...
Akshaya Srikanth Bhagavathula, Barun Ranjan Sarkar, Isha Patel   +2 more
doaj   +1 more source

Self-assessment in the implementation of pharmaceutical care in Indonesian hospitals [PDF]

, 2018
— Background: Pharmaceutical care is regarded as the process of optimizing the outcome of a patient’s drug therapy, thus improving the patient’s quality of life.
Setiadi, Antonius Adji Prayitno, Wardani, Susilo Ari, Wibowo, Ika Mulyono Putri, Wibowo, Yosi Irawati   +3 more
core  

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

The Impact of a Training Program on Clinical Pharmacists on Pharmacy Clinical Services in a Tertiary Hospital in Hunan China

Journal of Multidisciplinary Healthcare, 2019
Ping Xu,1 Yi Yun Hu,1 Hai Yan Yuan,1 Da Xiong Xiang,1 Yan Gang Zhou,1 Andrew J Cave,2 Hoan Linh Banh2 1Department of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410008, People’s Republic of China; 2Department ...
Xu P, Hu YY, Yuan HY, Xiang DX, Zhou YG, Cave AJ, Banh HL   +6 more
doaj  

ChatGPT and Clinical Training: Perception, Concerns, and Practice of Pharm-D Students

Journal of Multidisciplinary Healthcare, 2023
Mohammed Zawiah,1,2 Fahmi Y Al-Ashwal,3 Lobna Gharaibeh,4 Rana Abu Farha,5 Karem H Alzoubi,6,7 Khawla Abu Hammour,8 Qutaiba A Qasim,3 Fahd Abrah9 1Department of Clinical Pharmacy, College of Pharmacy, Northern Border University, Rafha, 91911, Saudi ...
Zawiah M, Al-Ashwal FY, Gharaibeh L, Abu Farha R, Alzoubi KH, Abu Hammour K, Qasim QA, Abrah F   +7 more
doaj  

Education in Pediatrics in US Colleges and Schools of Pharmacy [PDF]

, 2014
Objective. To determine the extent to which pediatrics is taught at US doctor of pharmacy (PharmD) programs and to characterize what is being taught and how. Methods.
Dahl, Elizabeth M., Hutchinson, David, Prescott, William Allan   +2 more
core   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source