Results 111 to 120 of about 10,510,072 (298)

Bioengineered Stroma‐Camouflaged Nanovesicles Disrupt the IDO1/CD276 Immunosuppressive Circuit to Reinvigorate Antitumor Immunity

Advanced Science, EarlyView.
Bioengineered stroma‐camouflaged nanovesicles (AM@UIO‐BMS/DOX) convert the immunosuppressive tumor niche into an immunoresponsive milieu by disrupting the IDO1/CD276 circuit. Anti‐CD276 membrane camouflage guides tumor accumulation and deep penetration, enabling controlled co‐delivery of DOX and the IDO1 inhibitor BMS‐986205.
Ziqi Zhang, Jing Luo, Mengdi Zhang, Jingying Zhuang, Yating Zheng, Yang Zhang, Zhihong Huang, Xinhua Lin, Shuzhen Xu, Hong Yao, Gang Liu, Bing Chen   +11 more
wiley   +1 more source

Pengelola dan Daftar Isi Pharmacy Vol. 14 No. 02 Desember 2017

, 2018
Pengelola dan Daftar Isi Pharmacy Vol. 14 No.
Pharmacy, Admin
core  

Targeting Nupr1‐Mediated p53 Mitochondrial Sequestration Alleviates Aortic Dissection by Restoring the Gadd45b‐Dependent Survival Program

Advanced Science, EarlyView.
This study identifies Nupr1 as a crucial stress‐responsive orchestrator driving AD. Under severe stress, Nupr1 massively accumulates within mitochondria to sequester p53, triggering apoptosis and concurrently repressing the Gadd45b‐mediated survival program.
Xi Yang, Ke‐Yuan Chen, Yue Tian, Zong‐Sheng Jiang, Jian Lei, Xing‐Hui Zhuang, Jiang‐Bin Wu, Le‐Le Tang, Hao‐Yu Li, Xiao‐Hui Chen, Yue Wang, Yu‐Mei Li, Zhi‐Huang Qiu, Zi‐Wen Cai, Liang‐Wan Chen   +14 more
wiley   +1 more source

Pengelola dan Daftar Isi Jurnal Pharmacy Vol. 13 No. 01 Juli 2016

, 2015
Pengelola dan Daftar Isi Jurnal Pharmacy Vol. 13 No.
Pharmacy, Admin
core  

Oral Actinomyces Species Exposure is Associated with Anxiety‐Like Behavior, Mitochondrial Remodeling, and Altered GABAergic Pathways

Advanced Science, EarlyView.
Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman, Zhenwu Luo, Douglas Johnson, Arshad A. Noorani, Zhuang Wan, Bogdan Bordieanu, Zhi‐wei Ye, Rachel D. Penrod, Hongxu Xian, Sylvia Fitting, Peter W. Kalivas, Wei Jiang   +11 more
wiley   +1 more source

Workforce development in community pharmacies in England: Opportunities and tensions for a private sector provider of NHS services.

PLoS ONE
BackgroundThe intention to more effectively mobilise and integrate the capabilities of the community pharmacy workforce within primary care is clearly stated within National Health Service (NHS) England policy.
Jayne L Astbury, Sally Jacobs, Imelda McDermott, Sarah C Willis, Aidan Moss, Selma Stearns, Catherine Fenton, Ali M K Hindi, Elizabeth M Seston, Ellen I Schafheutle   +9 more
doaj   +1 more source

Defining geriatric care in a developing country: A Multidisciplinary model empowering clinical pharmacists

Archives of Gerontology and Geriatrics Plus
Background: The elderly population often has complex health needs due to multimorbidity, polypharmacy, and inappropriate prescriptions. Clinical pharmacists play an important role in optimizing pharmacotherapy as a part of a multidisciplinary geriatric ...
Jehath Syed, Prathiba Pereira, Sri Harsha Chalasani, Madhan Ramesh, Tejeswini CJ, Shilpa Avarebeel, Kshama Ramesh, Ajay Sharma   +7 more
doaj   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

Advanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo, Katie Shi, Lina Kafadarian, Alexandra Bermudez, Johnny Diaz, Liam Edwards, Yunqi Hong, Ziyi Chen, Hyeonji Hwang, Weihong Yan, Alan Levinson, Robert Damoiseaux, Cho‐Jui Hsieh, Tanya Stoyanova, Andrew S. Goldstein, Neil Y.C. Lin   +15 more
wiley   +1 more source

Clinical Pharmacy Service — Who Needs It? [PDF]

Drug Intelligence & Clinical Pharmacy, 1975
openaire   +2 more sources

Pengelola dan Daftar Isi Jurnal Pharmacy Vol. 12 No. 02 Desember 2015

, 2015
Pengelola dan Daftar Isi Jurnal Pharmacy Vol. 12 No.
Pharmacy, Admin
core