Results 121 to 130 of about 10,510,072 (298)

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

open access: yesAdvanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi   +13 more
wiley   +1 more source

Assessing Public Awareness, Utilization and Satisfaction with Community Pharmacy Services

open access: yesPatient Preference and Adherence
Mansour M Alotaibi,1 Fai Y Almuharifi,2 Dina S Almuhaini,2 Dalya R Alsulaiman,2 Maryam A Albader,2 Wejdan A Alhejji,2 Fawaz M Alotaibi,3 Ibrahim M Asiri,3 Sawsan M Kurdi,3 Mohammed M Alsultan,3 Bassem A Almalki,3 Khalid A Alamer3 1Pharmacy Practice ...
Alotaibi MM   +11 more
doaj  

Indeks dan Panduan Penulis Pharmacy Vol. 14 No. 01 Juli 2017

open access: yes, 2018
Indeks dan Panduan Penulis Pharmacy Vol. 14 No.
Pharmacy, Admin
core  

Therapeutic Peptide‐Programmed Liquid‐Crystalline Topology Switching for pH‐Gated Postoperative Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan   +12 more
wiley   +1 more source

Survey of Potential Drug Interactions, Use of Non-Medical Health Products, and Immunization Status among Patients Receiving Targeted Therapies

open access: yesPharmaceuticals
In recent years, several changes have occurred in the management of chronic immunological conditions with the emerging use of targeted therapies. This two-phase cross-sectional study was conducted through structured in-person interviews in 2018–2019 and ...
Réka Rajj   +11 more
doaj   +1 more source

Home care pharmacy: extending clinical pharmacy services beyond infusion therapy.

open access: yes, 2000
Click on the Resource Link to access the article (may not be free).A clinical pharmacy program was developed at an established home health care (HHC) agency to demonstrate the need for clinical pharmacy services in the HHC population and to explore ...
Triller, Darren M   +5 more
core   +1 more source

In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He   +20 more
wiley   +1 more source

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

open access: yesAdvanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima   +18 more
wiley   +1 more source

Attributes and levels in discrete choice experiments for pharmacy services: A systematic review to inform asthma intervention design

open access: yesExploratory Research in Clinical and Social Pharmacy
Background: Asthma affects over 260 million people worldwide and remains poorly controlled. Pharmacists play an increasing role in management, yet evidence on which pharmacy service attributes patients value is limited.
Kanza Amalina Rosyida   +3 more
doaj   +1 more source

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