Results 121 to 130 of about 9,527,198 (297)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Reply to “Clinical practice guidelines or clinical research guidelines?” [PDF]

Clinical Neurophysiology, 2018
Baillet, Sylvain, Barnes, Gareth, Forss, Nina, Gross, Joachim, Hämäläinen, Matti, Jensen, Ole, Kakigi, Ryusuke, Mauguière, François, Nakasato, Nobukazu, Puce, Aina, Romani, Gian Luca, Schnitzler, Alfons, Taulu, Samu, Hari, Riitta   +14 more
openaire   +2 more sources

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Diagnosis and staging of patients with ovarian cancer: National Clinical Guideline No. 20

, 2019
This guideline is intended for all health professionals involved in the diagnosis and staging of patients with ovarian cancer and health professionals working in Genetics Services.
Department of Health
core  

First Iranian guidelines for the diagnosis, management, and treatment of hyperlipidemia in adults

Journal of Research in Medical Sciences
This guideline is the first Iranian guideline developed for the diagnosis, management, and treatment of hyperlipidemia in adults. The members of the guideline developing group (GDG) selected 9 relevant clinical questions and provided recommendations or ...
Fahimeh Bagheri Kholenjani, Shahla Shahidi, Golnaz Vaseghi, Vahid Ashoorion, Nizal Sarrafzadegan   +4 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Knowledge Translation Task Force for core measures clinical practice guideline: a short report on the process and utilization

Implementation Science Communications
Background As part of the 2018 Clinical Practice Guideline (CPG): A Core Set of Outcome Measures for Adults with Neurologic Conditions Undergoing Rehabilitation, a Knowledge Translation (KT) Task Force was convened.
Marghuretta D. Bland, Jennifer L. Moore, Elizabeth Anderl, Megan Eikenberry, Arlene McCarthy, Geneviève N. Olivier, Tracy Rice, Amelia Siles, Hallie Zeleznik, Wendy Romney   +9 more
doaj   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Implementability of clinical practice guidelines: the review and development of a Comprehensive Framework for Guideline Implementability (CFGI)

Implementation Science Communications
Introduction We define clinical practice guideline (CPGs) implementability as the characteristics of the guideline that reflect the extent to which it is likely to be adopted in clinical practice.
Dongmei Zhong, Yimin Wu, Gregory A Aarons, Alison M Hutchinson, William CW Wong, Sensen Lv, Zaiwei Song, Yanni Wu, David Makram Bishai, Ken Chen, Nan Yang, Yaolong Chen, Zhaolan Liu, Lijiao Yan, Pengxiang Zhou, Dong Roman Xu   +15 more
doaj   +1 more source