Results 91 to 100 of about 11,534,478 (301)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Longitudinal changes in body composition with advancing pregnancy and the relationship of maternal fat deposition to fetal growth. [PDF]

, 1996
Obesity has long been recognised as a risk factor for the development of variety of life threatening diseases; examples include diabetes mellitus and cardio vascular disease.
Soltani-Karbaschi, Hora, Soltani-Karbaschi, H.   +1 more
core   +3 more sources

The impact of long-acting Gonadotropin-releasing hormone agonist pretreatment on the clinical pregnancy outcomes of hormone replacement therapy-frozen embryo transfer in recurrent implantation failure patients with and without polycystic ovary syndrome: a retrospective clinical study

BMC Pregnancy and Childbirth
Background Several studies have demonstrated that pre-treatment with long-acting Gonadotropin-Releasing Hormone agonists (GnRHa) can significantly enhance the clinical pregnancy rate among recurrent implantation failure (RIF) patients.
Chenyang Huang, Yuan Yan, Jie Mei, Yue Jiang, Haixiang Sun, Jun Xing   +5 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Promoting positive adolescent sexual health & preventing teenage pregnancy - a review of recent effectiveness research

, 2004
This review was commissioned by the Crisis Pregnancy Agency to inform their work in the area of prevention of crisis pregnancy. The review commences with a brief description of the current epidemiological data on teenage pregnancy and adolescent ...
Fullerton, Deirdre
core  

Acute maternal exercise during the third trimester of pregnancy, influence on foetal heart rate = Ejercicio físico durante el tercer trimestre de embarazo, influencia en la frecuencia cardiaca fetal [PDF]

, 2008
A substantial amount of research has investigated the influence of physical exercise during pregnancy on certain maternal and foetal parameters. Regarding the behaviour of the foetal heart rate (FHR) during the maternal exercise certain controversy ...
Rubén Barakat Carballo, Stirling, James, Lucía Mulas, Alejandro, María Zakynthinaki, Zakynthinaki, María S., James Stirling, Barakat Carballo, Ruben, Alejandro Lucía Mulas   +7 more
core   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Effect of the time interval between denudation and ICSI on fresh embryo transfer reproductive outcomes: a retrospective study

Frontiers in Endocrinology
PurposeThis study aims to determine if the incubation after oocyte denudation before Intra-cytoplasmic sperm injection (ICSI) affects the clinical pregnancy rate.MethodsThis was a retrospective, consecutive data analysis of 1370 patients who underwent ...
Li Xiao, Li Xiao, Luqi Xue, Luqi Xue, Ju Zhang, Wei Fan, Wei Fan, Huili Zhu, Huili Zhu, Wei Huang, Wei Huang   +10 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Influence of Discordant Tubal Blockage on Clinical Pregnancy Rates: A Retrospective Cohort Study

Archives of Gynecology and Obstetrics
Abstract Purpose: To present recent data on discordant tubal blockage (DTB), its influence on pregnancy rates, and how women should gauge their fertility when screening and diagnostic tests don’t always agree. Methods: This retrospective cohort study included 78 infertile women, who underwent tubal patency assessment between January 2016 and ...
Franziska Elisabeth Bormann, Marlene Hager, Sophie Luise Thieme, John Preston Parry, Johannes Ott   +4 more
openaire   +2 more sources