Results 91 to 100 of about 8,340,302 (256)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Addendum clinical guideline screening and prioritisation criteria
, 2012 Clinical guideline prioritisation criteria are commonly utilised by various key international bodies and organisations in order to select clinical guidelines for development, appraisal or endorsement at national, regional and local level.
National Clinical Effectiveness Committee
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Challenges in the clinical development of orphan drugs [PDF]
, 2015 Rare diseases are characterised by a low prevalence. There are so many different rare diseases, that millions of people are affected.The vast majority of these diseases suffer from a lack of approved treatment options and orphan drugs (ODs) therefore ...
Pharmacoepidemiology and Clinical Pharmacology +2 more
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Global HeartBackground: Heart failure (HF) affects approximately 64.3 million people worldwide. Despite notable progress over the past two decades in advancing the understanding of heart failure in Africa–a condition often more lethal than many cancers–important ...
Karen Sliwa +11 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Clinical medication review: one step beyond: Computer rules of personal goals? [PDF]
, 2019 In this ageing society, older persons are using more and more medications for chronic diseases. During a clinical medication review, the community pharmacist evaluate all the medication use together with the patient in a personal conversation.
Verdoorn, Marguerita Alexandra +2 more
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International Journal of Integrated Health SciencesObjectives: To study epidemiological characteristics, clinical features, laboratory findings, and clinical outcomes in cases of scrub typhus. Additionally, the study aims to identify the predictors of disease severity.
A. V. Dahiphle +4 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Clinical profile of participants.
, 2016 Clinical profile of participants.
Sneha Chenji (2847707) +6 more
core +1 more source
Student's Journal of Health Research AfricaBackground Poisoning remains a significant public health issue in developing countries, contributing to substantial morbidity and mortality. Identifying patterns and prevalent substances involved is essential for guiding preventive measures and clinical
Dr. Tejasvi J +2 more
doaj +1 more source