Results 101 to 110 of about 8,340,302 (256)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical profile of recurrent vesicular palmoplantar dermatitis in children and adolescents

open access: yes, 2019
Hugo Guimarães Scotelaro-Alves,1 Nurimar Conceição Fernandes,2 Marcia Ramos-e-Silva3 1Sector of Dermatology, Post-Graduation Program in Medical Clinics, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil;
Scotelaro-Alves HG   +2 more
core  

Pharmacokinetics of novel anticancer drugs and dynamics of circulating tumor cells in early clinical studies [PDF]

open access: yes, 2011
Cancer has an enormous impact on the lives of patients and on society and there is an urgent need for improvements in therapy. In this thesis, early-clinical studies into both safety and pharmacokinetics of novel anti-cancer drugs as well as into ...
Devriese, L.A.   +2 more
core   +1 more source

A Study on Etiology, Risk Factors, and Clinical Profile of Spontaneous Pneumothorax: A Single-Center Experience from South India

open access: yesIndian Journal of Medical Specialities
Introduction: Spontaneous pneumothorax (SP) commonly presents as continuous, sharp, unilateral chest pain exacerbated by deep inspiration and change of posture.
N. Gopichand   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Clinical Characteristics and Drug Resistance Profile of Mycobacterium colombiense Infection: A Study of 22 Cases [PDF]

open access: yes
Lin Mei,1,2,* Feng Liang,1,* Shengsheng Liu,2 Hua Chen1 1Guangzhou Chest Hospital, Guangzhou, People’s Republic of China; 2Department of Tuberculosis, Anhui Chest Hospital, Hefei, People’s Republic of China*These authors ...
Mei L, Liang F, Liu S, Chen H
core  

Clinical trends and mycological profile of tinea corporis et cruris: A cross-sectional study in a tertiary care center

open access: yesJournal of Dr. NTR University of Health Sciences
Background: Tinea corporis et cruris is a major category of superficial dermatophytosis, forming the bulk of routine dermatology ailments. However, in recent years, an epidemic-like scenario of dermatophytosis has emerged with increased incidence of ...
Rhonda Latsaheb   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

National Clinical Effectiveness Committee annual report 2013

open access: yes, 2014
The National Clinical Effectiveness Committee (NCEC) was established as part of the Patient Safety First Initiative in September 2010. The NCECs mission is to provide a framework for national endorsement of clinical guidelines and audit to optimise ...
National Clinical Effectiveness Committee
core  

Clinical profile and outcomes analysis of HIV infection

open access: yes
Background India has the third largest number of human immunodeficiency virus (HIV) patients, but the national prevalence is continuously receding owing to dedicated health centers as well as highly active antiretroviral therapy (HAART), which is ...
Yoganathan Chidambaram   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy