Results 191 to 200 of about 8,340,302 (256)

Clinical Profile, Management Strategies, and Outcomes of Children with Multiple Magnet Ingestion: A Retrospective Case Series. [PDF]

J Indian Assoc Pediatr Surg
Aggerwal N, Vibhash C, Singh UB, Mishra P, Solanki A.   +4 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Epidemiological and clinical profile of patients with liver hydatid cyst in an endemic region. [PDF]

BMC Surg
Ameen SHH.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Distinguishing Chronic and Non-Chronic Depression: A Clinical Profile and Symptom Networks Approach.

Psychother Psychosom
Rehm P, Gruber M, Ahrens KF, Staub H, Timm F, Krätzig L, Fischer S, Edwin Thanarajah S, Berg M, Goltermann J, Winter NR, Thiel K, Borgers T, Meinert H, Bonnekoh LM, Flinkenflügel K, Bauer J, Stein F, Thomas-Odenthal F, Usemann P, Teutenberg L, Nenadić I, Straube B, Alexander N, Jamalabadi H, Jansen A, Opel N, Meinert S, Grotegerd D, Hahn T, Leehr EJ, Schramm E, Elsaesser M, Rief W, Reif A, Kircher T, Dannlowski U, Repple J.   +37 more
europepmc   +1 more source

Clinical profile and outcome of road traffic accidents among adult patients treated at urban government hospitals in Ethiopia. [PDF]

Afr J Emerg Med
Amare A, Getu R, Debalkew B, Jegnie M, Azazh A.   +4 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Clinical Profile of Elderly Atopic Dermatitis in China. [PDF]

Clin Cosmet Investig Dermatol
Wu M, Li F, Xu G, Chen X, Zhang Y, Yao X.   +5 more
europepmc   +1 more source