Results 201 to 210 of about 2,749,598 (311)

Developmental origin and clinical profile of siamese twins in a tertiary care setting. [PDF]

Bioinformation
Tiwari A, Singh B, Nigam A, Gupta VK, Nema P.   +4 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Etiology, clinical profile, management, and outcomes of intestinal obstruction in a resource-limited setting: a prospective study. [PDF]

Sci Rep
Alashaby SS, Gilan WM, Al-Absy TA, Al-Magedi AAS.   +3 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Epidemiological Trends and Clinical Profile of Dengue in Assam: A Retrospective Analysis From 2022 to 2025. [PDF]

Cureus
Sarmah H, Bhattacharya S, Brahma D, Majumdar S, Gogoi J, Rasul ES.   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Clinical Profile of Ectopic Pregnancy in a Tertiary Care Center: A Five-Year Retrospective Study. [PDF]

JNMA J Nepal Med Assoc
Chudal D, Shrestha A, Manandhar R, Thakur S, Kharel D, Shrestha U, Basnet B.   +6 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Clinical Profile of Giant Cell Arteritis and Polymyalgia Rheumatica in a Tertiary Care Hospital in South India. [PDF]

Cureus
George N A, Gopal M, Mathew J, Goel R, Thomas M.   +4 more
europepmc   +1 more source