Results 41 to 50 of about 8,340,302 (256)
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Background: Idiopathic intracranial hypertension (IIH) has been increasing in prevalence in the past decade, following the obesity epidemic. When medical treatment fails, surgical treatment options must be considered.
Arielle Spitze +4 more
doaj +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
HSE National Centre for Clinical Audit Clinical Audit – A Practical Guide
This document replaces the previously published “A Practical Guide to Clinical Audit” (HSE 2013). It forms part of a series of resources being developed to support services and all healthcare professionals to ensure the continuation and development of ...
HSE National Centre for Clinical Audit
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Background: Atrial fibrillation (AF) being the most common arrhythmia encountered clinically is associated with increased mortality and morbidity. Hence, this study was conducted to find the clinical profile, etiology, and echocardiographic factors of AF
Abdul Mateen Athar +3 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Aleksandra Zarska,1 Stephanie Slat,1 Adrianne Kehne,1,2 Colin Macleod,1 Heather Rye,3 Cheryl Dehmlow,4 Paul Hilliard,5 Kaitlyn Jaffe,6 Pooja Lagisetty1,2 1Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; 2Center for Clinical ...
Dehmlow C +8 more
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