Results 141 to 150 of about 2,207,856 (261)

Parenting Intervention for Psychological Flexibility and Emotion Regulation: Clinical Protocol and an Evidence-Based Case Study. [PDF]

Int J Environ Res Public Health, 2022
Flujas-Contreras JM, García-Palacios A, Gómez I.   +2 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Clinical protocol for nutritional screening in autism (PANA): a cross-sectional study protocol. [PDF]

BMJ Open
Vaz JDS, Valle SC, Silva ES, Hoffmann LV, Luçardo J, Maia JC, Magalhães LVDS, Castro K.   +7 more
europepmc   +1 more source

Intranasal Dexmedetomidine as Sedative for Medical Imaging in Young Children: A Systematic Review to Provide a Roadmap for an Evidence-Guided Clinical Protocol. [PDF]

Children (Basel), 2022
Hermans K, Ramaekers L, Toelen J, Vanhonsebrouck K, Allegaert K.   +4 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Insertable cardiac monitor-guided early intervention to reduce atrial fibrillation burden following catheter ablation: Study design and clinical protocol (ICM-REDUCE-AF trial). [PDF]

Ann Noninvasive Electrocardiol, 2023
Tankut SS, Huang DT, Zareba W, Aktas MK, Rosero SZ, Steinberg J, Henchen J, Kutyifa V, Strawderman RL, Goldenberg I.   +9 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Machine stability and dosimetry for ultra-high dose rate FLASH radiotherapy human clinical protocol. [PDF]

J Appl Clin Med Phys
Gonçalves Jorge P, Geyer R, Kinj R, Schiappacasse L, Jeanneret-Sozzi W, Bourhis J, Herrera F, Bochud F, Bailat C, Moeckli R.   +9 more
europepmc   +1 more source

Utility Of An Emergency Department Clinical Protocol For Early Identification of Coronavirus Infection. [PDF]

West J Emerg Med, 2021
Bonadio W, Jackson K, Gottlieb L, Legome E.   +3 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source