Results 61 to 70 of about 15,228,231 (351)

Protocol for the quantitative detection of mtDNA in the supernatants of activated human naive CD8+ T cells

STAR Protocols
Summary: Here, we present a protocol for the quantitative characterization of human T cell aging. We describe steps for sample collection; peripheral blood mononuclear cell (PBMC) isolation; and the enrichment, assessment, and activation of naive CD8+ T ...
Linlin Li, Jun Jin
doaj   +1 more source

Protocol for building a cognitive map of structural knowledge in humans by integrating abstract relationships from separate experiences

STAR Protocols, 2021
Summary: Humans are adept at learning the latent structure of the relationship between abstract concepts and can build a cognitive map from limited experiences.
Seongmin A. Park, Douglas S. Miller, Erie D. Boorman   +2 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Protocol for detecting homologous recombination activity in cancer cells by adenovirus-based functional assay

STAR Protocols
Summary: Cancer cells with homologous recombination deficiency (HRD) exhibit a distinctive vulnerability to poly(ADP-ribose) polymerase inhibitors (PARPis).
Shih-Han Huang, Chih-Ying Lee, Peter Chi
doaj   +1 more source

ABM Clinical Protocol #9: Use of Galactogogues in Initiating or Augmenting Maternal Milk Production, Second Revision 2018

Breastfeeding Medicine, 2018
A central goal of the Academy of Breastfeeding Medicine is the development of clinical protocols for managing common medical problems that may impact breastfeeding success.
Wendy Brodribb
semanticscholar   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Optimizing diagnostic and management pathways for patients with eosinophilia of unknown origin: a multidisciplinary protocol for urgent and non-urgent evaluation

Frontiers in Medicine
IntroductionPersistent eosinophilia of unknown cause is a key feature of numerous health disorders. These conditions present diagnostic and management challenges, often leading to delayed treatment, increased morbidity and mortality and unnecessary ...
Silvia Sánchez-Ramón, Gloria Candelas Rodríguez, Jesús Gimeno Hernández, María Luisa González Gutiérrez, Sissy Fiorella Medina Salazar, Manuel Méndez Bailón, Begoña Navas Elorza, Ángel Nieto Sánchez, Teresa Robledo Echarren, Santiago Rueda Esteban, Marcos Oliver Fragiel Saavedra, María Dolores Zamora Barrios, Cristina Martínez Prada, Celina Benavente Cuesta, Celia Pinedo Sierra, EOS Multidisciplinary Group   +15 more
doaj   +1 more source

Análise do perfil de solicitações para transfusão de hemocomponentes no Hospital de Clínicas de Porto Alegre no ano de 2005 Blood-based products request profile analysis in Hospital de Clínicas de Porto Alegre in 2005

Revista Brasileira de Hematologia e Hemoterapia, 2008
O uso de hemocomponentes em hospitais de alta complexidade é elevado, sendo necessário controle e racionalização de sua utilização, dada sua escassez e alto custo. Para tal, muitos hospitais desenvolveram protocolos para uso de hemocomponentes.
Leo Sekine, Letícia F. Wirth, Gustavo A. M. Faulhaber, Beatriz G. S. Seligman   +3 more
doaj   +1 more source

Comparing clinical outcomes of patients with severe lower limb trauma undergoing orthoplastic and orthopedic surgeries: A long-term study protocol

Heliyon
This long-term study protocol aims to compare the clinical outcomes of patients with severe lower limb trauma undergoing orthoplastic and orthopedic surgeries, focusing on their physical and psychological status.
Zhao Yang, Chao Xu, Yonggang Zhu, Yanchen Tan, Hao Hu, Peng Fang, Di Cui, Guang-Yue Zhao, Danmin Miao, Lei Shang   +9 more
semanticscholar   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source