Results 81 to 90 of about 15,228,231 (351)
Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
British medical journal, 2020 Objective To develop and validate a pragmatic risk score to predict mortality in patients admitted to hospital with coronavirus disease 2019 (covid-19). Design Prospective observational cohort study.S. Knight, A. Ho, R. Pius, I. Buchan, G. Carson, T. Drake, J. Dunning, C. Fairfield, C. Gamble, C. A. Green, Rishi K. Gupta, S. Halpin, H. Hardwick, K. Holden, P. Horby, C. Jackson, K. McLean, L. Merson, J. Nguyen-Van-Tam, Lisa Norman, M. Noursadeghi, P. Olliaro, M. Pritchard, C. Russell, Catherine A Shaw, Aziz Sheikh, Tommy Solomon, C. Sudlow, O. Swann, L. Turtle, P. Openshaw, J. Baillie, M. Semple, A. Docherty, E. Harrison, J. Baillie, M. Semple, P. Openshaw, G. Carson, B. Alex, Benjamin Bach, W. Barclay, D. Bogaert, M. Chand, Graham S. Cooke, A. Docherty, J. Dunning, A. da Silva Filipe, T. Fletcher, C. A. Green, E. Harrison, J. Hiscox, A. Ho, P. Horby, S. Ijaz, S. Khoo, P. Klenerman, Andrew Law, W. Lim, A. Mentzer, L. Merson, A. Meynert, M. Noursadeghi, S. Moore, M. Palmarini, W. Paxton, G. Pollakis, NicholasS . C. Price, A. Rambaut, David L. Robertson, C. Russell, V. Sancho-Shimizu, J. Scott, L. Sigfrid, Tommy Solomon, S. Sriskandan, D. Stuart, C. Summers, R. Tedder, E. Thomson, R. Thwaites, L. Turtle, M. Zambon, H. Hardwick, C. Donohue, Jane Ewins, W. Oosthuyzen, Fiona Griffiths, Lisa Norman, R. Pius, Tom M. Drake, C. Fairfield, S. Knight, K. McLean, D. Murphy, Catherine A Shaw, J. Dalton, M. Girvan, Eglė Savičiūtė, S. Roberts, Janet R Harrison, Laura Marsh, M. Connor, S. Halpin, C. Jackson, C. Gamble, G. Leeming, Ross Hendry, James Scott-Brown, W. Greenhalf, V. Shaw, Sarah E. McDonald, K. Ahmed, J. Armstrong, M. Ashworth, I. G. Asiimwe, Siddharth Bakshi, S. Barlow, Laura J. Booth, B. Brennan, K. Bullock, Benjamin W. A. Catterall, Jordan J. Clark, Emily Clarke, Sarah J. Cole, L. Cooper, H. Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, P. Dyer, A. Elliott, A. Evans, Lewis W S Fisher, T. Foster, Isabel García-Dorival, W. Greenhalf, P. Gunning, Catherine Hartley, A. Ho, R. L. Jensen, Christopher Jones, T. R. Jones, Shadia Khandaker, K. King, Robyn T Kiy, Chrysa Koukorava, Annette Lake, S. Lant, D. Latawiec, L. Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A. Livoti, Maria Mancini, L. McEvoy, J. Mclauchlan, S. Metelmann, Nahida Miah, J. Middleton, Joyce Mitchell, E. Murphy, R. Penrice-Randal, J. Pilgrim, T. Prince, W. Reynolds, P. Ridley, Debby Sales, V. Shaw, R. Shears, B. Small, Krishanthi S Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, E. Trochu, Libby van Tonder, Eve Wilcock, J. Zhang, K. Adeniji, D. Agranoff, K. Agwuh, D. Ail, A. Alegria, Brian Angus, A. Ashish, Doug Atkinson, S. Bari, G. Barlow, S. Barnass, Nicholas A. Barrett, C. Bassford, D. Baxter, M. Beadsworth, J. Bernatoniene, J. Berridge, N. Best, P. Bothma, D. Brealey, R. Brittain-Long, N. Bulteel, Thomas G Burden, A. Burtenshaw, Vikki Caruth, D. Chadwick, D. Chambler, Nigel Chee, J. Child, S. Chukkambotla, Tom Clark, P. Collini, Catherine Cosgrove, J. Cupitt, Maria-Teresa Cutino-Moguel, P. Dark, Chris Dawson, S. Dervisevic, P. Donnison, S. Douthwaite, I. DuRand, A. Dushianthan, Tristan Dyer, C. Evans, C. Eziefula, C. Fegan, A. Finn, D. Fullerton, S. Garg, A. Garg, J. Godden, A. Goldsmith, Clive Graham, E. Hardy, S. Hartshorn, D. Harvey, P. Havalda, D. Hawcutt, M. Hobrok, L. Hodgson, Anita Holme, A. Hormis, M. Jacobs, Susan Jain, P. Jennings, A. Kaliappan, V. Kasipandian, S. Kegg, Michael R. Kelsey, J. Kendall, C. Kerrison, I. Kerslake, O. Koch, G. Koduri, G. Koshy, S. Laha, Susan G. Larkin, T. Leiner, P. Lillie, James Limb, V. Linnett, J. Little, M. MacMahon, E. Macnaughton, Ravish Mankregod, Huw Masson, E. Matovu, K. McCullough, R. Mcewen, M. Meda, G. Mills, J. Minton, M. Mirfenderesky, K. Mohandas, Quen Mok, J. Moon, Elinoor Moore, P. Morgan, C. Morris, K. Mortimore, S. Moses, Mbiye A Mpenge, Rohinton Mulla, Michael J. Murphy, Megan L. Nagel, T. Nagarajan, M. Nelson, I. Otahal, M. Pais, S. Panchatsharam, Hassan Paraiso, B. Patel, J. Pepperell, M. Peters, M. Phull, S. Pintus, J. Pooni, F. Post, D. Price, R. Prout, N. Rae, H. Reschreiter, Tim Reynolds, Neil Richardson, M. Roberts, D. Roberts, A. Rose, G. Rousseau, Brendan J. Ryan, Taranprit Saluja, A. Shah, Prad Shanmuga, Anil Sharma, A. Shawcross, J. Sizer, Richard Smith, C. Snelson, N. Spittle, N. Staines, T. Stambach, R. Stewart, P. Subudhi, T. Szakmany, K. Tatham, Jordan Thomas, C. Thompson, R. Thompson, A. Tridente, D. Tupper-Carey, M. Twagira, A. Ustianowski, N. Vallotton, L. Vincent-Smith, S. Visuvanathan, A. Vuylsteke, S. Waddy, R. Wake, A. Walden, I. Welters, T. Whitehouse, P. Whittaker, A. Whittington, M. Wijesinghe, Martin Williams, Lawrence Wilson, S. Wilson, S. Winchester, M. Wiselka, A. Wolverson, D. Wooton, A. Workman, B. Yates, Peter Young +352 moresemanticscholar +1 more sourceFinancial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb +8 morewiley +1 more sourceHealthcare professional’s guide to cardiopulmonary exercise testing [PDF]
, 2015 Cardiopulmonary exercise testing (CPEX) is a valuable clinical tool that has proven indications within the fields of cardiovascular, respiratory and pre-operative medical care.Frenneaux, Michael P., Gollop, Nicholas D., Loudon, Brodie L., Parasuraman, Sathish, Schwarz, Konstantin +4 morecore +1 more sourceHydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
International Journal of Antimicrobial Agents, 2020 Background Chloroquine and hydroxychloroquine have been found to be efficient on SARS-CoV-2, and reported to be efficient in Chinese COV-19 patients. We evaluate the effect of hydroxychloroquine on respiratory viral loads.P. Gautret, J. Lagier, P. Parola, V. Hoang, L. Meddeb, M. Mailhe, B. Doudier, J. Courjon, V. Giordanengo, V. E. Vieira, H. Tissot Dupont, S. Honoré, P. Colson, E. Chabrière, B. La Scola, J. Rolain, P. Brouqui, D. Raoult +17 moresemanticscholar +1 more sourceThe Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods
We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler +17 morewiley +1 more sourceFeatures of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol
medRxiv, 2020 Objective: To characterize the clinical features of patients with severe COVID-19 in the UK. Design: Prospective observational cohort study with rapid data gathering and near real-time analysis, using a pre-approved questionnaire adopted by the WHO ...A. Docherty, E. Harrison, C. A. Green, H. Hardwick, R. Pius, Lisa Norman, K. Holden, Jonathan M. Read, F. Dondelinger, G. Carson, L. Merson, James Lee, Daniel R Plotkin, L. Sigfrid, S. Halpin, C. Jackson, Carrol Gamble, Peter Horby, J. Nguyen-Van-Tam, Jake Dunning, P. Openshaw, J. K. Baillie, M. Semple +22 moresemanticscholar +1 more sourceFeasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose
Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere +15 morewiley +1 more sourcePrimary HIV-1 Infection Among Infants in sub-Saharan Africa: HPTN 024. [PDF]
, 2009 Our objectives were to assess clinical signs and diagnoses associated with primary HIV-1 infection among infants. We analyzed data from a clinical trial (HIV Prevention Trials Network Protocol 024) in sub-Saharan Africa.Anthony Mwatha, Barbra Richardson, Bollinger, Boom, Chasela, Daar, Guay, Hecht, Horwood, Irving Hoffman, Jennifer S Read, Jones, Kahn, Karim Manji, Kinloch-de Loes, Lavreys, Lepage, Lynda Emel, Megan Valentine, Nozyce, Richardson, Robert L Goldenberg, Rouet, Schacker, Taha, Taha E Taha, Usha Sharma +26 morecore +2 more sources