Results 161 to 170 of about 1,341,814 (306)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Proteus – A Model for Clinical Protocols Created from Knowledge Components

open access: yes, 2008
We describe a model – Proteus, for clinical protocols created with clinical knowledge represented as components. By applying principles of distributed computing the knowledge can be managed by experts at other locations while it is available to the ...
Hemant Shah
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Proteus - A Model for Clinical Protocols Created from Knowledge Components

open access: yes, 2001
We describe a model -- Proteus, for clinical protocols created with clinical knowledge represented as components. By applying principles of distributed computing the knowledge can be managed by experts at other locations while it is available to the ...
Hemant Shah
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

The LEAP checklist for laboratory evaluation and analytical performance characteristics reporting of clinical measurement procedures

open access: yes
Reporting a measurement procedure and its analytical performance following method evaluation in a peer-reviewed journal is an important means for clinical laboratory practitioners to share their findings.
Zakaria, Rosita,   +8 more
core   +1 more source

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