Results 171 to 180 of about 2,012,129 (303)

Dose-Dependent Analysis of Image Quality in Pediatric Head CT Scans Across Different Scanners to Optimize Clinical Protocols Using Phantom-Based Assessment. [PDF]

Tomography
Kuwahara H, Ojima M, Kawamura T, Saitou D, Andou K, Ariga E, Hasegawa K, Kai M.   +7 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Prevention and Management of Stroke After Transcatheter Aortic Valve Replacement: The Mount Sinai Stroke Initiative

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Sahil Khera, Anoop N. Koshy, Gilbert H. L. Tang, Pedro Moreno, Roxana Mehran, George D. Dangas, David Bronster, Annapoorna S. Kini, Michael Fara, Samin K. Sharma   +9 more
doaj   +1 more source

Neurorehabilitation of Visual Neglect: A Narrative Review of Approaches from A.R. Luria to Modern Clinical Protocols. [PDF]

Consort Psychiatr
Stepanov G, Terentiy D, Propustina V, Skvortsov A, Kovyazina M, Varako N, Bukinich A, Vasyura E.   +7 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Sekundarna depresija kod alkoholičara - klinički značaj [PDF]

Vojnosanitetski Pregled, 2005
Mandić-Gajić Gordana
doaj   +1 more source

Society for Immunotherapy of Cancer (SITC) consensus statement on essential biomarkers for immunotherapy clinical protocols. [PDF]

J Immunother Cancer
Cottrell TR, Lotze MT, Ali A, Bifulco CB, Capitini CM, Chow LQM, Cillo AR, Collyar D, Cope L, Deutsch JS, Dubrovsky G, Gnjatic S, Goh D, Halabi S, Kohanbash G, Maecker HT, Maleki Vareki S, Mullin S, Seliger B, Taube J, Vos W, Yeong J, Anderson KG, Bruno TC, Chiuzan C, Diaz-Padilla I, Garrett-Mayer E, Glitza Oliva IC, Grandi P, Hill EG, Hobbs BP, Najjar YG, Pettit Nassi P, Simons VH, Subudhi SK, Sullivan RJ, Takimoto CH.   +36 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Reverse pharmacology based clinical protocols for noninvasive integrative management of low grade cervical precancer lesions: Rationale and outcomes. [PDF]

J Ayurveda Integr Med
Joshi JV, Raut AA, Paradkar PH, Jagtap SS.   +3 more
europepmc   +1 more source

Effects of differences between peer reviewers suggested by authors and by editors - Reply [PDF]

, 2006
Black, N, Hutchings, A, Schroter, S, Tite, L   +3 more
core   +1 more source