Results 51 to 60 of about 1,341,814 (306)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Comparison of two different protocols for the induction of maturation of human dendritic cells in vitro [PDF]

Vojnosanitetski Pregled, 2004
Background. Dendritic cells (DC) have been used for immunotherapy of malignant tumors, different kinds of infections, and other clinical conditions. For that purpose, optimal conditions for the generation of functionally mature DC in vitro are required ...
Čolić Miodrag J., Mojsilović Slavko, Pavlović Bojan, Vučićević Dragana, Majstorović Ivana, Bufan Biljana, Stojić-Vukanić Zorica, Vasilijić Saša, Vučević Dragana, Gašić Sonja, Balint Bela J.   +10 more
doaj   +1 more source

: Comparative Evaluation of Different Protocols

, 2003
Disease-associated gene polymorphisms provide both scientific insight into pathophysiological mechanisms and clinical information regarding risk and progression.
Ingelsson, M, Forsell, C, Lena Lilius, Irizarry, MC, Youngah Shin, Graff, C,, Lilius, L,, Bradley T. Hyman, Hyman, BT, Charlotte Forsell, Caroline Graff, Shin, Y, Martin Ingelsson, Michael C. Irizarry   +13 more
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Clinicopathological characteristics, diagnosis and treatment of melanoma in Serbia: The Melanoma Focus Study [PDF]

Vojnosanitetski Pregled, 2015
Background/Aim. Treatment options for metastatic melanoma in Serbia are limited due to the lack of newly approved biologic agents and the lack of clinical studies.
Kandolf-Sekulović Lidija, Babović Nada, Balić Mirjana, Nikolin Borislava, Nikolić Dejan, Janjić Zlata, Jokić Neven, Mijušković Željko, Rajović Milica, Novaković Marijan, Vrbić Svetislav, Pejčić Ivica, Kovačević Predrag, Mihajlović Dragan, Roganović Tatjana, Ferenc Vicko, Nikolić Jelena, Marinković Marija, Bizetić Zorana   +18 more
doaj   +1 more source

Opiate Detoxification Protocols: A Clinical Manual

, 1993
The purpose of any opiate detoxification protocol is to minimize or eliminate the signs and symptoms associated with opiate withdrawal, thereby decreasing the chances of relapse to opiate dependence.
Cutler, Robert, Fishbain, David A, Rosomoff, Hubert L, Rosomoff, Renee Steele   +3 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

India Hypertension Control Initiative: Blood Pressure Control Using Drug and Dose-Specific Standard Treatment Protocol at Scale in Punjab and Maharashtra, India, 2022

Global Heart
Background: Hypertension treatment coverage is low in India. A stepwise simple treatment protocol is one of the strategies to improve hypertension treatment in primary care.
Prabhdeep Kaur, Manikandanesan Sakthivel, Vettrichelvan Venkatasamy, Padmaja Jogewar, Sandeep S. Gill, Abhishek Kunwar, Meenakshi Sharma, Anupam Khungar Pathni, Kiran Durgad, Swagata Kumar Sahoo, Amol Wankhede, Navneet Kumar, Vishwajit Bharadwaj, Bidisha Das, Tejpalsinh Chavan, Suhas Khedkar, Lalit Sarode, Sampada D. Bangar, Ashish Krishna, Roopa Shivashankar, Parasuraman Ganeshkumar, Pragati Pragya, Balram Bhargava   +22 more
doaj   +1 more source

Management of germ cell tumors in children: Approaches to cure [PDF]

, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Schneider, D. T., P. Schmidt, Schmidt, P., Haas, R. J., Göbel, U., R.J. Haas, U. Goebel, G. Calaminus, D.T. Schneider, Calaminus, G.   +9 more
core   +1 more source