Results 71 to 80 of about 1,341,814 (306)

Aggressive Pharmacotherapy in Reproductive Medicine. Pregnancy and Medicines (Author’s Perspective)

Безопасность и риск фармакотерапии
The article discusses the issues of polypharmacy and unjustified prescribing in pregnant women. The author— Honoured Scientist of the Russian Federation, Corresponding Member of the Russian Academy of Sciences, Doctor of Medical Sciences, Full Professor,
V. E. Radzinskiy
doaj   +1 more source

Promoting public access to clinical trial protocols: challenges and recommendations [PDF]

, 2018
Background Recognizing the value of promoting public access to clinical trial protocols, Trials pioneered the way for their publication over a decade ago.
Asbjørn Hróbjartsson, Chan, An Wen, An-Wen Chan, Chan, An-Wen, Hróbjartsson, Asbjørn   +4 more
core   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Clinical Protocols PHC Remote

, 2018
The key purpose of these clinical protocols is to provide the authorised Clinical Protocols and Procedures Manuals and Additional Clinical protocols available for Primary Health Care remote clinicians to guide clinical practice.

core  

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Integrated Simulation Framework for Toxicity, Dose Intensity, Disease Progression, and Cost Effectiveness for Castration-Resistant Prostate Cancer Treatment with Eribulin

, 2015
Quantitative model-based analyses are helpful to support decision-making in drug development. In oncology, disease progression/clinical outcome (DPCO) models have been used for early predictions of clinical outcome, but most of such approaches did not ...
Schellens, J. H M, Huitema, A. D. R., Pharmacoepidemiology and Clinical Pharmacology, Beijnen, J. H., Hussein, Z., Sub Clinical Pharmacology, Gupta, A., Van Hasselt, J. G C   +7 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Advancing pre-hospital emergency nursing care: Formulating a Clinical Protocol for Aluminum Phosphide Poisoning (CPALP) [PDF]

Nursing and Midwifery Studies
Background: Aluminum phosphide (ALP) poisoning is a critical health issue that poses significant challenges for pre-hospital emergency responders.Objectives: This study aims to develop a clinical protocol for managing ALP poisoning in pre-hospital ...
Omid Alipour Shirazi, Ravanbakhsh Esmaeili, Zakaria Zakariaei, Mohammad Hosseini-Nejad, Mahmood Moosazadeh, Shayan Alijanpour   +5 more
doaj   +1 more source

Temporal Knowledge Representation for Scheduling Tasks in Clinical Trial Protocols

, 2002
Clinical trial protocols include detailed temporal constraints on treatment and associated tasks. Unlike health-care guidelines, protocols are highly prescriptive.
Weng, C., Gennari, John H, Kahn, M.
core  

Ethical and scientific considerations for patient enrollment into concurrent clinical trials. [PDF]

, 2014
Researchers and institutional review boards often consider it inappropriate for patients to be asked to consent to more than one study despite there being no regulatory prohibition on co-enrollment in most countries.
Williamson, Elizabeth, Oakley, Justin, Justin Oakley, Andrew Forbes, Myles, Paul S, Elizabeth Williamson, Forbes, Andrew, Paul S Myles   +7 more
core   +1 more source