Results 141 to 150 of about 60,396,491 (305)

An Investigation into the Current Landscape, Challenges, and Training Imperatives of Clinical Research Among Anesthesiologists in China

Risk Management and Healthcare Policy
Yingjie Du,1,* Ruirong Chen,1,* Lili Wu,1 Quan Chen,2 Tiankuo Yu,1 He Li,1 Guyan Wang1 1Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Anesthesiology, The ...
Du Y, Chen R, Wu L, Chen Q, Yu T, Li H, Wang G   +6 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A conversation with Kevin Gibbs, MD, associate professor, Wake Forest University School of Medicine

Journal of Clinical and Translational Science
Clinical Research Forum
doaj   +1 more source

Trajectory analysis in clinical research. [PDF]

Clin Kidney J
D'Arrigo G, Gori M, Chesnaye NC, Jager KJ, Dekker FW, van Diepen M, Zoccali C, Tripepi G.   +7 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Conversation with Waldemar A. Carlo, MD, Co-Division Director of Neonatology, Edwin M. Dixon Chair in Neonatology Professor of Pediatrics, University of Alabama at Birmingham

Journal of Clinical and Translational Science
Clinical Research Forum
doaj   +1 more source

Clinical research updates

Child and Adolescent Mental Health, 2022
Marinos Kyriakopoulos, Panagiota Chrysikopoulou, Dionisios Vallianatos, Evi Drosopoulou   +3 more
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A conversation with Mehdi Shishehbor, DO, MPH, PhD, President, Harrington Heart & Vascular Institute and Professor of Medicine, Cleveland University Hospitals Cleveland Medical Center

Journal of Clinical and Translational Science
Clinical Research Forum
doaj   +1 more source

Clinical research is not an optional extra. [PDF]

Clin Med (Lond)
Solomon T.
europepmc   +1 more source