Results 161 to 170 of about 60,396,491 (305)

Collective Equipoise, Disappointment and the Therapeutic Misconception: On the Consequences of Selection for Clinical Research [PDF]

Private information induces individuals to self-select as subjects into clinical research trials, and it induces researchers to select which trials they conduct.
Margaret M. Byrne, Peter Thompson
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A conversation with Dr. Kevin Magnaye, Data Scientist, Caris Life Sciences

Journal of Clinical and Translational Science
Clinical Research Forum
doaj   +1 more source

The deployment of ProKnow for cloud-based clinical research in radiotherapy. [PDF]

PLOS Digit Health
Anagnostatou V, Knauer M, Maier SH, Winderl T, Reiner M, Thasler R, Corradini S, Niyazi M, Hinske LC, Belka C, Schönecker S.   +10 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A conversation with Loren Miller, MD, MPH, professor and chief, Division of Infectious Diseases, Lundquist Institute at Harbor-UCLA

Journal of Clinical and Translational Science
Clinical Research Forum
doaj   +1 more source

A narrative review of clinical research on knee osteoarthritis in 2025. [PDF]

Ann Jt
Lv J, Hu C, Zhang H, Ou T, Shi D, Lv Z.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

A conversation with Jonathan M. Davis, MD, Vice-chair of Pediatrics, Tufts Medical Center, Tufts University School of Medicine

Journal of Clinical and Translational Science
Clinical Research Forum
doaj   +1 more source

Clinical research updates

Child and Adolescent Mental Health, 2019
openaire   +10 more sources