Results 81 to 90 of about 60,396,491 (305)

Irish Health Research Forum meeting. Theme: should Ireland set health research priorities? [PDF]

open access: yes, 2018
This report presents the proceedings of the Irish Health Research Forum on May 21st, 2018 focusing on the topic of whether Ireland should set health research ...
Medical Research Charities Group
core  

Central Challenges Facing the National Clinical Research Enterprise

open access: yes, 2003
Medical scientists and public health policy makers are increasingly concerned that the scientific discoveries of the past generation are failing to be translated efficiently into tangible human benefit.
Catanese, Veronica   +18 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Chinese expert consensus on the diagnosis and treatment of leptomeningeal metastasis from breast cancer

open access: yesZhongguo aizheng zazhi
Leptomeningeal metastasis from breast cancer is one of the severe complications of advanced breast cancer, characterized by complex and variable clinical manifestations, rapid disease progression, and an extremely poor prognosis.
Clinical Cancer Research Evaluation Committee of Chinese Medical Education Association   +1 more
doaj   +2 more sources

Cardiovascular research in CLINICS

open access: yesClinics, 2013
CLINICS is a multidisciplinary medical journal. This editorial highlights the field of cardiovascular research. We have selected papers published from 2011-2012 and focused on the concept of Continuously Variable Rating, which we have recently introduced as an alternative and hopefully superior method for evaluating published scientific papers (1).
openaire   +5 more sources

Clinical Psychology Today Vol 4 Issue 1 (Summer 2020)

open access: yes, 2020
'Clinical Psychology Today' a journal for Clinical Psychologists to share research, practice and exchange views on the science and practice of Clinical Psychology.
White, Lynn, Collins, Padraig
core  

GDPR and health research: stakeholder voices. Data protection and health research - what does the legislation mean for patients, the public and the research community? Report and recommendations. [PDF]

open access: yes, 2018
This report presents the proceedings of the Irish Health Research Forum on November 14th 2018 focusing on data protection legislation and health research, and the implications for patients, the public and researchers.
Medical Research Charities Group
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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