Results 161 to 170 of about 12,286,608 (353)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Comparative clinical evaluation of safety and efficacy of commonly used drug-eluting stents in coronary artery disease patients after angioplasty in South India: A retro-prospective multi-center study [PDF]

, 2019
Vinoth Prabhu Veeramani, Saranya Selvam, Ahmed M. Hamdan, Vinoth Prabhu Veeramani, M Barton, J Gruntzig, M Husmann, J Rosch, E Benjamin, M Blaha, S Chiuve, M Cushman, S Das, R Deo, S De Ferranti, J Floyd, M Fornage, C Gillespie, C Isasi, M Jimenez, L Jordan, S Judd, D Lackland, J Lichtman, L Lisabeth, S Liu, C Longenecker, R Mackey, K Matsushita, D Mozaffarian, M Mussolino, K Nasir, R Neumar, L Palaniappan, D Pandey, R Thiagarajan, M Reeves, M Ritchey, C Rodriguez, G Roth, W Rosamond, C Sasson, A Towfighi, C Tsao, M Turner, S Virani, J Voeks, J Willey, J Wilkins, J Wu, H Alger, S Wong, P Muntner, J Feinberg, E Nielsen, J Greenhalgh, J Hounsome, N Sethi, S Safi, C Gluud, J Jakobsen, R Gupta, W Kim, S Lee, S Park, Y Kim, S Yun, J Lee, D Park, S Kang, C Lee, J Lee, S Choi, I Seong, B Lee, N Lee, Y Cho, W Shin, S Lee, S Lee, M Hyon, D Bang, W Park, H Kim, J Chae, K Lee, H Park, C Park, S Lee, M Kim, K Park, Y Choi, S Cheong, T Yang, J Jang, S Her, S Park, P Karjalainen, A Ylitalo, J Airaksinen   +99 more
openalex   +1 more source

Decision letter for "Entrepreneurship and nurse entrepreneurs lead the way to the development of nurses’ role and professional identity in clinical practice: A qualitative study"

, 2021

openalex   +1 more source

[Retracted] Effect of Dapagliflozin on Clinical Outcome after Drug‐Eluting Stent Implantation in Elderly T2DM Patients: A Real‐World Study [PDF]

, 2023
Yuan Lin, Fang Zhou, Xihu Wang, Yaju Guo, Weiguo Chen   +4 more
openalex   +1 more source

Data privacy by design: digital infrastructures for clinical collaborations

, 2009
The clinical sciences have arguably the most stringent security demands on the adoption and roll-out of collaborative e-Infrastructure solutions such as those based upon Grid-based middleware.
Ajayi, O., Sinnott, R.O., Stell, A.J.
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Design and Evaluation of Using Head-Mounted Virtual Reality for Learning Clinical Procedures: Mixed Methods Study (Preprint)

, 2023
Siew Tiang Lau, Chiew Jiat Rosalind Siah, Khairul Dzakirin Bin Rusli, Wen Liang Loh, John Yap, Emily Ang, Fui Ping Lim, Sok Ying Liaw   +7 more
openalex   +1 more source

Clinical comparative study of glasses-free 3D and 2D thoracoscopic surgery in minimally invasive esophagectomy [PDF]

, 2022
Rongqiang Wei, Xinyu Ding, Zihao Chen, Ning Xin, Chengdong Liu, Yunhao Fang, Zhifei Xu, Kenan Huang, Hua Tang   +8 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Clinical Manifestations, Diagnosis and Management of Synovial Fistula Associated Lateral Ankle Sprain or Instability: A Retrospective Study of 19 Surgically Confirmed Patients [PDF]

, 2022
Jahyung Kim, Bum-Jin Shim, Jae-Shin Yang, Altanzul Bat-Ulzii, Jaeho Cho   +4 more
openalex   +1 more source