Results 291 to 300 of about 2,097,719 (347)

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

open access: yesAdvanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu   +7 more
wiley   +1 more source

Clinical markers of thrombolytic success

European Heart Journal, 1996
Although a number of markers of successful coronary thrombolysis have been proposed, only a few of these have the two necessary features of a clinically useful marker: (1) widespread early availability and (2) good predictive value. The reduction in ST-segment elevation on the standard 12 lead electrocardiogram 1-4 h after initiation of thrombolysis ...
V, Pasceri, F, Andreotti, A, Maseri
openaire   +2 more sources

Strategies for Successful Clinical Teaching

AJN, American Journal of Nursing, 2016
This article is one in a series on the roles of adjunct clinical faculty and preceptors, who teach nursing students and new graduates to apply knowledge in clinical settings. This article describes teaching strategies as well as the importance of the learning environment.
Linda, Koharchik, Sharon R, Redding
openaire   +2 more sources

Monoclonal antibody successes in the clinic

Nature Biotechnology, 2005
Most monoclonal antibodies in clinical trials are owned by small biotech companies. But with blockbuster-sized revenues and approval rates higher than those for small-molecule drugs, that all may be set to change.
Janice M, Reichert   +3 more
openaire   +2 more sources

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