Results 291 to 300 of about 2,097,719 (347)
Targeting RNA with synthetic oligonucleotides: Clinical success invites new challenges. [PDF]
Hofman CR, Corey DR.
europepmc +1 more source
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu +7 more
wiley +1 more source
Clinical success of anti-infective combination therapy compare to monotherapy in patients with carbapenem-resistant Pseudomonas aeruginosa infection: a 10-years retrospective study. [PDF]
Chen J, Lin J, Weng J, Ju Y, Li Y.
europepmc +1 more source
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Clinical markers of thrombolytic success
European Heart Journal, 1996Although a number of markers of successful coronary thrombolysis have been proposed, only a few of these have the two necessary features of a clinically useful marker: (1) widespread early availability and (2) good predictive value. The reduction in ST-segment elevation on the standard 12 lead electrocardiogram 1-4 h after initiation of thrombolysis ...
V, Pasceri, F, Andreotti, A, Maseri
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Strategies for Successful Clinical Teaching
AJN, American Journal of Nursing, 2016This article is one in a series on the roles of adjunct clinical faculty and preceptors, who teach nursing students and new graduates to apply knowledge in clinical settings. This article describes teaching strategies as well as the importance of the learning environment.
Linda, Koharchik, Sharon R, Redding
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Monoclonal antibody successes in the clinic
Nature Biotechnology, 2005Most monoclonal antibodies in clinical trials are owned by small biotech companies. But with blockbuster-sized revenues and approval rates higher than those for small-molecule drugs, that all may be set to change.
Janice M, Reichert +3 more
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