Results 141 to 150 of about 13,113,839 (405)
A Latent Gaussian Process Model with Application to Monitoring Clinical Trials [PDF]
arXiv, 2014 In many clinical trials treatments need to be repeatedly applied as diseases relapse frequently after remission over a long period of time (e.g., 35 weeks). Most research in statistics focuses on the overall trial design, such as sample size and power calculation, or on the data analysis after trials are completed.
arxiv
Barriers to Clinical Trial Enrollment in Racial and Ethnic Minority Patients With Cancer.
Cancer Control: Journal of the Moffitt Cancer Cente, 2016 BACKGROUND Clinical trials that study cancer are essential for testing the safety and effectiveness of promising treatments, but most people with cancer never enroll in a clinical trial - a challenge exemplified in racial and ethnic minorities ...
L. Hamel +5 more
semanticscholar +1 more source
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
From RAGs to riches: Utilizing large language models to write documents for clinical trials [PDF]
Clinical Trials: Journal of the Society for Clinical Trials (2025)
-- online ahead of printThis manuscript has now been published: - Link to article on journal website: https://journals.sagepub.com/doi/10.1177/17407745251320806 - Pubmed link: https://pubmed.ncbi.nlm.nih.gov/40013826/
arxiv +1 more source
Journal of Clinical Oncology, 2016 PURPOSE To provide recommendations on appropriate clinical trial designs in non-muscle-invasive bladder cancer (NMIBC) based on current literature and expert consensus of the International Bladder Cancer Group.
A. Kamat +10 more
semanticscholar +1 more source
Clinical trials in dermatology
International Journal of Women's Dermatology, 2017 Clinical trials are the backbone of modern day medicine. Randomized, double-blinded, placebo-controlled studies are critical for advancement in medicine and dermatology. Skin conditions such as psoriasis and atopic dermatitis are among the most common health problems in the United States.
Kristin Torre, Mona Shahriari
openaire +4 more sources
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Pediatric InvestigationImportance Pediatric medication is a challenging issue globally. Promoting trials of medications for children and implementing measures to encourage innovation for addressing unmet medical and health needs are important.
Chang Liu +4 more
doaj +1 more source
Panacea: A foundation model for clinical trial search, summarization, design, and recruitment [PDF]
arXivClinical trials are fundamental in developing new drugs, medical devices, and treatments. However, they are often time-consuming and have low success rates. Although there have been initial attempts to create large language models (LLMs) for clinical trial design and patient-trial matching, these models remain task-specific and not adaptable to diverse
arxiv