Results 141 to 150 of about 3,635,661 (309)

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Electrophysiology’s Identity Crisis: What our Clinical Trials Do and Do Not Say About Us

Arrhythmia & Electrophysiology Review, 2020
David J Callans, Matthew Reynolds, Peter J Zimetbaum   +2 more
doaj   +1 more source

Endoscopic lavage after intraventricular haemorrhage in neonates in the UK (ENLIVEN-UK): study protocol for a national randomised-controlled trial

Trials
Background Intraventricular haemorrhage (IVH) is a common and severe complication of preterm birth, affecting nearly 500 neonates annually in the UK.
Saniya Mediratta, Aswin Chari, Cheryl Battersby, Patrick Bauserman, Emilia Caverly, William Dawes, Hakim-Moulay Dehbi, Andrew Embleton-Thirsk, Laurence Galland, Gregory James, Sally Jary, Charlotte Kelham, Alyson MacNeil, Sue Massingham, Neil Marlow, Amalia Ndoutoumou, Monica Panca, Victoria Pittordou, Cristine Sortica da Costa, Andrew Whitelaw, Conor Mallucci, Kristian Aquilina   +21 more
doaj   +1 more source

E-health and consultation rates for respiratory illnesses in infants: a randomised clinical trial in primary care [PDF]

, 2015
Anne C. van der Gugten, Cuno S.P.M. Uiterwaal, Theo Verheij, Cornelis K. van der Ent   +3 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

ModerateDrinking.Com and moderation management: Outcomes of a randomized clinical trial with non-dependent problem drinkers.

, 2011
Reid K. Hester, Harold D. Delaney, William Campbell   +2 more
openalex   +2 more sources

Preclinical study and clinical trial of a novel therapeutic vaccine against multi-drug resistant tuberculosis [PDF]

, 2016
Masaji Okada, Yoko Kita, Satomi Hashimoto, Hitoshi Nakatani, Shiho Nishimastu, Yumiko Kioka, Yasuko Takami   +6 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Prevalence and Characteristics of Interventional Trials Conducted Exclusively in Elderly Persons: A Cross-Sectional Analysis of Registered Clinical Trials

, 2016
Florence T. Bourgeois, Karen L. Olson, Tony Tse, John P. A. Ioannidis, Kenneth D. Mandl   +4 more
openalex   +2 more sources

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source