Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Advances in Clinical Trials of Boron Neutron Capture Therapy. [PDF]
Research (Wash D C)Li X, Liu Z, Liu K, Wang C, Liu Z, Xu X.
europepmc +1 more source
Efficacy of luseogliflozin for renal function preservation in patients with type 2 diabetes mellitus and impaired renal function: A randomized open‐label clinical trial (
Mari Kitada +25 more
openalex +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Clinical Trials on Atrial Fibrillation in Asia: Where Are We Now. [PDF]
JACC AsiaKong X, Yang Z, Ma C.
europepmc +1 more source
Clinical outcomes, cost-effectiveness and implementation of individualised physiotherapy using the Specific Treatment Of Problems of the Spine (STOPS) approach for chronic low back pain in Nigeria: a protocol for a prospective sequential clinical trial [PDF]
Musa Sani Danazumi +3 more
openalex +1 more source
Growing Diversity in Data Science: Shared Lessons from Clinical Trials [PDF]
, 2019 Simari, Robert D.
core +2 more sources
Clinical trial registration [PDF]
Rheumatology, 2008 Watts, R. A., Cubie, S.
openaire +2 more sources
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source