Results 261 to 270 of about 14,066,519 (402)

Supplementary Materials for "Investigation of a clinical trial drug VV261 as a potent antiviral candidate against Chikungunya virus"

Yumin Zhang, Sheng Tang, Lu Chen
openalex   +1 more source

Bone Remodeling Around Implants with External Hexagon and Morse‐Taper Connections: A Randomized, Controlled, Split‐Mouth, Clinical Trial

, 2016
Roberto Sales e Pessoa, Ravel Sousa, Leandro Maruki Pereira, Flávio Domingues das Neves, Fábio Bezerra, Siegfried Jaecques, J. Van der Sloten, Marc Quirynen, Wim Teughels, Rubens Spin‐Neto   +9 more
openalex   +2 more sources

Increasing Diversity in Clinical Trials: Overcoming Critical Barriers.

Current problems in cardiology, 2019
Luther T Clark, L. Watkins, I. Piña, M. Elmer, O. Akinboboye, M. Gorham, B. Jamerson, Cassandra McCullough, C. Pierre, A. Polis, G. Puckrein, Jeanne M. Regnante   +11 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Representation of Older Adult Patients in Clinical Trials. [PDF]

Clin Transl Sci
Haertter S, Mallalieu NL, Saleh S, Goldsmith P, Sane R, Cook J.   +5 more
europepmc   +1 more source

Clinical medication review by a pharmacist of patients on repeat prescriptions in general practice: a randomised controlled trial

, 2002
Arnold Zermansky, DR Petty, DK Raynor, CJ Minns Lowe, Nick Freemantle, Andy Vail   +5 more
openalex   +2 more sources

Limitations of Animal Studies for Predicting Toxicity in Clinical Trials

JACC: Basic to Translational Science, 2019
Gail A. Van Norman
semanticscholar   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The Effects of Resilience Training on the Self-Efficacy of Patients with Type 2 Diabetes: A Randomized Controlled Clinical Trial.

, 2019
Camellia Torabizadeh, Zahra Asadabadi Poor, Maryam Shaygan   +2 more
openalex   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source