How do systematic reviews incorporate risk of bias assessments into the synthesis of evidence? A methodological study [PDF]
, 2014 Background: Systematic reviews (SRs) are expected to critically appraise included studies and privilege those at lowest risk of bias (RoB) in the synthesis.
Egan, Matt +2 more
core +2 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Cell therapy of periodontium: from animal to human?
Frontiers in Physiology, 2013 Periodontitis is a chronic inflammatory disease affecting the soft and hard tissues supporting the teeth, which often leads to tooth loss. Its significant impact on the patient’s general health and quality of life point to a need for more effective ...
Elena Andreea eTrofin +3 more
doaj +1 more source
Involving clinical experts in prioritising topics for health technology assessment: a randomised controlled trial [PDF]
, 2017 Andrew Cook, Elke Streit, Gill Davage
openalex +1 more source
Successful private–public funding of paediatric medicines research: lessons from the EU programme to fund research into off-patent medicines [PDF]
, 2014 The European Paediatric Regulation mandated the European Commission to fund research on off-patent medicines with demonstrated therapeutic interest for children.
Baiardi, P +17 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Frontiers in Psychology, 2015 According to the literature, psychological assessment in forensic contexts is one of the most controversial application areas for clinical psychology. This paper presents a review of systematic judgment errors in the forensic field.
Antonio eIudici +3 more
doaj +1 more source
The UK clinical research network - has it been a success for dermatology clinical trials?
Trials, 2011 BackgroundFollowing the successful introduction of five topic-specific research networks in the UK, the Comprehensive Local Research Network (CLRN) was established in 2008 in order to provide a blanket level of support across the whole country regardless
K. Thomas +5 more
semanticscholar +1 more source
Efecto de las intervenciones no invasivas en el bienestar y la calidad de vida de los pacientes con cáncer de pulmón: resultados de una revisión sistemática [PDF]
, 2006 Aim: To highlight the results of a systematic review on the effect of non-invasive interventions delivered to lung cancer patients in improving their well-being and quality of life.
Solà, Iván, Subirana, Mireia
core +1 more source
Graph-Sparse LDA: A Topic Model with Structured Sparsity [PDF]
, 2014 Originally designed to model text, topic modeling has become a powerful tool for uncovering latent structure in domains including medicine, finance, and vision.
Adams, Ryan +2 more
core +1 more source