Results 301 to 310 of about 635,069 (409)

Basket trials in rare diseases: a systematic review of current practices, methodological challenges, and future directions. [PDF]

Orphanet J Rare Dis
Khazen W, Corriol-Rohou S, Evangelista T, Valent A, Abbas S, Nissan X, Mejat A.   +6 more
europepmc   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Editorial: Mechanisms and strategies to overcome antibiotic resistance in gastrointestinal pathogens. [PDF]

Front Antibiot
da Silva TF, Grygorcewicz B.
europepmc   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Assessing uptake of the macular degeneration core outcome set in clinical trials: a cross-sectional study. [PDF]

BMJ Open
Oldham E, Hall RH, Jones G, Modi J, Ward S, Magee T, Fitzgerald K, Magana K, Hughes G, Ford AI, Vassar M.   +10 more
europepmc   +1 more source

A scoping review of interventions to prevent and treat adverse events during treatment of rifampin-susceptible tuberculosis. [PDF]

PLoS One
Burman WJ, Martins MF, Flynn D, Johnston J, Sinha P, Horsburgh CR.   +5 more
europepmc   +1 more source

Introduction and Methodology: Standards of Care in Diabetes-2026. [PDF]

Diabetes Care
American Diabetes Association Professional Practice Committee for Diabetes* .
europepmc   +1 more source