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Topical Silymarin Cream as a Novel Therapy Versus Salicylic Acid Peels in Acne Vulgaris: A Split-Face Clinical Trial

Journal of Cutaneous Medicine and Surgery, 2023
Background Acne vulgaris is a common dermatological condition that greatly impacts patients’ self-confidence. Ongoing research is conducted to explore new treatment modalities. Silymarin owns special characteristics that qualify it as a possible treatment for acne vulgaris.
Dalia Abdel-Aziz Atallah   +3 more
openaire   +2 more sources

Amphotericin as a Topical Antifungal Antibiotic

A.M.A. Archives of Dermatology, 1959
A previously unknown Streptomyces species, isolated from a soil sample obtained at Tembladora, on the Orinoco River in South America, has been found to produce two amphoteric antifungal agents which have been named amphotericin A and amphotericin B. 1 Studies of their physical properties reveal slight differences between the infrared absorption spectra
W M, FRASER, J M, KNOX
openaire   +2 more sources

The Clinical Efficacy of EMLA as a Topical Anesthetic Agent Instead of Palatal Injection During Maxillary Dental Extractions: A Randomized Controlled Trial

Journal of Maxillofacial and Oral Surgery, 2021
Even after the invention of the modern injection techniques, palatal injection still remains a painful experience for patients, and this pain is attributed to the presence of rich nerve complement and displacement of tightly adherent palatal mucosa during anesthesia.To check the clinical efficacy of EMLA as a topical anesthetic agent instead of palatal
Ankita Chugh   +6 more
openaire   +2 more sources

Topical minocycline microspheres versus topical chlorhexidine gel as an adjunct to mechanical debridement of incipient peri‐implant infections: a randomized clinical trial

Journal of Clinical Periodontology, 2006
AbstractAim: This randomized clinical trial presents a 12‐month follow‐up of the clinical and microbiological results after application of minocycline microspheres as an adjunct to mechanical treatment of incipient peri‐implant infections compared with an adjunctive treatment using 1% chlorhexidine gel application.Material and Methods: Thirty‐two ...
Stefan, Renvert   +4 more
openaire   +2 more sources

Efficacy and safety of calcipotriol as a potential topical treatment of acne vulgaris: a randomized, controlled, triple blinded, split-face clinical trial

Clinical and Experimental Dermatology, 2023
Abstract Background Acne vulgaris is a common skin problem that may result in significant scarring and systemic comorbidities. Adverse effects and increasing resistance to available treatments urge the development of new therapeutics.
Ayman Mahran   +3 more
openaire   +2 more sources

Selective laser trabeculoplasty versus topical medication as initial glaucoma treatment: the glaucoma initial treatment study randomised clinical trial

British Journal of Ophthalmology, 2019
Background/AimsTo determine if selective laser trabeculoplasty (SLT) is superior to topical medication as a first-line treatment for glaucoma on quality of life (QoL) and clinical outcomes.MethodsIn this international, longitudinal, multisite randomised controlled trial, treatment naïve mild-to-moderate primary open angle or exfoliation glaucoma ...
Ghee Soon Ang   +19 more
openaire   +3 more sources

Topical herbal application as an adjuvant treatment for chronic kidney disease – a systematic review of randomized controlled clinical trials

Journal of Advanced Nursing, 2012
zhang h., ho y.f., che c.‐t., lin z.‐x., leung c. & chan l.s. (2012) Topical herbal application as an adjuvant treatment for chronic kidney disease – a systematic review of randomized controlled clinical trials. Journal of Advanced Nursing68(6), 1679–1691.AbstractAim.  To report a systematic review to evaluate whether topical herbal medicine delays
Hongwei, Zhang   +5 more
openaire   +2 more sources

Sex Bias in Interventional Clinical Trials

Journal of Women's Health, 2018
Introduction: Prior studies have shown that sex bias exists with subject enrollment in clinical trials, with more men being enrolled than women. The objective of this study was to identify if sex bias continues to exist in present day clinical trials ...
Vivek S. Prakash   +4 more
semanticscholar   +1 more source

Topical ketorolac as an adjunctive treatment with intravitreal bevacizumab in the management of diabetic macular edema: A double-masked placebo-controlled randomized clinical trial

Graefe's Archive for Clinical and Experimental Ophthalmology, 2021
To evaluate the additional effect of ketorolac eye drops on therapeutic effects of intravitreal Bevacizumab in patients with diabetic macular edema (DME) METHODS: In a randomized clinical trial, 50 patients with center involved DME (macular thickness ≥ 300 microns accompanied by decreased VA (24 
Homayoun Nikkhah   +6 more
openaire   +2 more sources

A pilot clinical trial testing topical resiquimod and a xenopeptide as immune adjuvants for a melanoma vaccine targeting MART-1

Melanoma Research, 2019
A vaccine that could expand melanoma-specific T cells might reduce the risk of recurrence of resected melanoma and could provide an alternative or adjunct to standard immunotherapy options. We tested the safety and immunogenicity of a vaccine coupling a melanoma-associated peptide with a xenogenic peptide (to promote epitope spreading) and/or ...
Matthew S, Block   +5 more
openaire   +2 more sources

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