Results 1 to 10 of about 41,480 (249)

RESEARCH ETHICS COMMITTEES (RECs) AND MONITORING OF BIOMEDICAL RESEARCH IN PAKISTAN

Khyber Medical University Journal, 2013
Global health is facing enormous challenges and medical research is the only way to cope with these challenges. Worldwide, extensive clinical research is being conducted in all fields of medicineto resolve the health related issues through best available
Akhtar Sherin
doaj  

Undertaking Studies Within A Trial to evaluate recruitment and retention strategies for randomised controlled trials: lessons learnt from the PROMETHEUS research programme

Health Technology Assessment
Background Randomised controlled trials (‘trials’) are susceptible to poor participant recruitment and retention. Studies Within A Trial are the strongest methods for testing the effectiveness of strategies to improve recruitment and retention.
Adwoa Parker, Catherine Arundel, Laura Clark, Elizabeth Coleman, Laura Doherty, Catherine Elizabeth Hewitt, David Beard, Peter Bower, Cindy Cooper, Lucy Culliford, Declan Devane, Richard Emsley, Sandra Eldridge, Sandra Galvin, Katie Gillies, Alan Montgomery, Christopher J Sutton, Shaun Treweek, David J Torgerson   +18 more
doaj   +1 more source

THE ETHICAL STARTUP?

Voices in Bioethics
Photo ID 345549 © Jonathan Mulkey | Dreamstime.com Abstract Emerging DNA marketplace startups aim to empower individuals with greater control and potential profit-sharing over their genetic data, but they face ethical tensions in navigating ...
Alexis Walker
doaj   +1 more source

Allopurinol and cardiovascular outcomes in patients with ischaemic heart disease: the ALL-HEART RCT and economic evaluation

Health Technology Assessment
Background Allopurinol is a xanthine oxidase inhibitor that lowers serum uric acid and is used to prevent acute gout flares in patients with gout.
Isla S Mackenzie, Christopher J Hawkey, Ian Ford, Nicola Greenlaw, Filippo Pigazzani, Amy Rogers, Allan D Struthers, Alan G Begg, Li Wei, Anthony J Avery, Jaspal S Taggar, Andrew Walker, Suzanne L Duce, Rebecca J Barr, Jennifer S Dumbleton, Evelien D Rooke, Jonathan N Townend, Lewis D Ritchie, Thomas M MacDonald   +18 more
doaj   +1 more source

Recommendations for data monitoring committees from the Clinical Trials Transformation Initiative [PDF]

Clinical Trials, 2017
Background/aims Use of data monitoring committees to oversee clinical trials was first proposed nearly 50 years ago. Since then, data monitoring committee use in clinical trials has increased and evolved. Nonetheless, there are no well-defined criteria for determining the need for a data monitoring committee ...
Jane Perlmutter, David Demets
exaly   +5 more sources

Data monitoring committees for clinical trials evaluating treatments of COVID-19

Contemporary Clinical Trials, 2020
The first cases of coronavirus disease 2019 (COVID-19) were reported in December 2019 and the outbreak of SARS-CoV-2 was declared a pandemic in March 2020 by the World Health Organization. This sparked a plethora of investigations into diagnostics and vaccination for SARS-CoV-2, as well as treatments for COVID-19.
Tim Friede
exaly   +5 more sources

Data monitoring committees for multicenter clinical trials sponsored by the national institutes of health

Contemporary Clinical Trials, 1991
Barbara S Hawkins
exaly   +2 more sources

Data monitoring committees in pediatric randomized controlled trials registered in ClinicalTrials.gov

Clinical Trials, 2023
Tiago Machado, Daniel Caldeira, Beatrice Mainoli   +2 more
exaly  

Older adult participation in cancer clinical trials: A systematic review of barriers and interventions

Ca-A Cancer Journal for Clinicians, 2021
William Tew, Gretchen Kimmick, William Dale   +2 more
exaly  

Views on Emerging Issues Pertaining to Data Monitoring Committees for Adaptive Trials

Therapeutic Innovation and Regulatory Science, 2013
Christy Chuang-Stein, Sandeep Menon, Paul Gallo   +2 more
exaly