Results 11 to 20 of about 29,514,683 (309)

"You have to keep your nerve on a DMC." Challenges for Data Monitoring Committees in neonatal intensive care trials: Qualitative accounts from the BRACELET Study.

PLoS ONE, 2018
BackgroundData Monitoring Committees (DMCs) are essential to the good conduct of many trials. Typically they comprise a small expert group which monitors safety, efficacy, progress and early outcome data as trials recruit.
Claire Snowdon, Peter Brocklehurst, Robert C Tasker, Martin Ward Platt, Diana Elbourne   +4 more
doaj   +2 more sources

Charting the content of data monitoring committee charters for clinical trials. [PDF]

Clin Trials
Background: Data monitoring committees play a critical role in ensuring the ethical conduct of clinical trials. Data monitoring committee charters set out the role and processes for data monitoring committees in monitoring clinical trials; however, little is known about the information charters contain.
Eckstein L, Ibrahim A, Orr O, Rid A, Shah SK.   +4 more
europepmc   +3 more sources

Approach to the state of the art of data monitoring committees in clinical trials

Revista Cubana de Medicina Militar, 2021
Introduction: For the first time, in 1967, a data monitoring committee was established in a study of cardiovascular mortality. Since then its use has increased, due to its value to guarantee the safety of subjects participating in clinical trials, the ...
Sonia Pérez Rodríguez, Héctor Lázaro Lara Fernández, Selma Arteaga Cantón, Meiby de la Caridad Rodríguez González, Maura Tamayo Rodríguez   +4 more
doaj   +1 more source

Data Monitoring Committees in Clinical Trials: A Practical Perspective

The American Statistician, 2022
C. Barker
openaire   +2 more sources

Data monitoring committees and randomized clinical trials

Kidney International, 2019
Howard, Trachtman, Arthur L, Caplan
openaire   +3 more sources

Safety and data monitoring committees for clinical trials [PDF]

Clinical Cardiology, 1995
C. Richard Conti
openaire   +3 more sources

Data monitoring committees: Promoting best practices to address emerging challenges

Clinical Trials, 2017
Background and Purpose: Data monitoring committees are responsible for safeguarding the interests of study participants and assuring the integrity and credibility of clinical trials.
T. Fleming, D. DeMets, M. Roe, J. Wittes, K. Calis, A. Vora, A. Meisel, Raymond P. Bain, M. Konstam, M. Pencina, David J. Gordon, K. Mahaffey, C. Hennekens, J. Neaton, G. Pearson, T. Andersson, M. Pfeffer, S. Ellenberg   +17 more
semanticscholar   +2 more sources

Data and Safety Monitoring Committees in Clinical Trials

Journal of the Royal Statistical Society Series A: Statistics in Society, 2010
A. Rehman
openaire   +2 more sources

Moving fast but going slow: coordination challenges for trials of COVID-19 post-exposure prophylaxis

Trials, 2020
An unprecedented volume of research has been generated in response to the COVID-19 pandemic. However, there are risks of inefficient duplication and of important work being impeded if efforts are not synchronized.
Darrell H. S. Tan, Rupesh Agrawal, Ruanne V. Barnabas, Jon T. Giles, Peter Dull   +4 more
doaj   +1 more source

Comprehensive Survey of Clinical Trials Registration for Melanoma Immunotherapy in the ClinicalTrials.gov

Frontiers in Pharmacology, 2020
Objective: Comprehensively evaluate the immunotherapeutic clinical trials and provide reference for melanoma treatment and research.Methods: The website of ClinicalTrials.gov was searched to retrieve and download all registered clinical trials for ...
Yan-Bo Wang, Gang Lv, Feng-Hua Xu, Lin-Lu Ma, Yong-Ming Yao   +4 more
doaj   +1 more source