Results 271 to 280 of about 29,514,683 (309)

A Practical Guide to Data Monitoring Committees in Adaptive Trials

Therapeutic Innovation and Regulatory Science, 2014
Christy Chuang-Stein, Sandeep Menon, Paul Gallo   +2 more
exaly   +2 more sources

Data monitoring committees, interim analysis and early termination in paediatric trials

Acta Paediatrica, International Journal of Paediatrics, 2011
Martin Offringa, Ricardo M Fernandes
exaly   +2 more sources

Data and Safety Monitoring Committees in Clinical Trials

2009
Jay Herson, Jay Herson
openaire   +2 more sources

Proceedings of the University of Pennsylvania 10th annual conference on statistical issues in clinical trials: Current issues regarding Data and Safety Monitoring Committees in clinical trials

Clinical Trials, 2018
This issue of Clinical Trials contains the proceedings of the tenth annual conference on statistical issues in clinical trials, held at the University of Pennsylvania in April 2017.
S. Ellenberg, J. Ellenberg
semanticscholar   +1 more source

Bringing data monitoring committee charters into the sunlight

Clinical Trials, 2023
Clinical trials investigating novel or high risk interventions, or studying vulnerable participants, often use a data monitoring committee to oversee the progress of the trial.
D. DeMets, D. Zarin, F. Rockhold, S. Ellenberg, Thomas Fleming, J. Wittes   +5 more
semanticscholar   +1 more source

Decision Analysis for a Data Monitoring Committee of a Clinical Trial

1998
A data monitoring committee holds a position of great trust within the structure of a US clinical trial, as it alone receives the accumulating data and decides whether to continue the trial. The committee generally meets at regularly scheduled intervals, e.g. six months.
Joseph B. Kadane, Pantelis Vlachos, Samuel Wieand   +2 more
openaire   +1 more source

University of Pennsylvania 10th annual conference on statistical issues in clinical trials: Current issues regarding data and safety monitoring committees in clinical trials (morning panel session)

Clinical Trials, 2018
Barry R. Davis, David Kerr, M. Maguire, Corsee Sanders, S. Snapinn, J. Wittes   +5 more
semanticscholar   +1 more source

Enhancing the Scientific Integrity and Safety of Clinical Trials: Recommendations for Data Monitoring Committees.

Journal of the American Medical Association (JAMA), 2016
R. Lewis, K. Calis, D. DeMets
semanticscholar   +1 more source

Clinical Trials of Herpes Simplex Encephalitis: The Role of the Data Monitoring Committee

2006
Herpes simplex encephalitis (HSE) is the most frequent cause of focal necrotizing encephalitis, accounting for approximately 2,500 cases annually in the United States. Studies initiated in the early 1970s have continuously evaluated promising antiviral drugs for the treatment of this disease, utilizing randomized, blinded, controlled clinical trial ...
openaire   +1 more source

Data monitoring committees for multicenter clinical trials sponsored by the National Institutes of Health. I. Roles and membership of data monitoring committees for trials sponsored by the National Eye Institute.

Controlled Clinical Trials, 1991
B. Hawkins
semanticscholar   +1 more source